CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identification

E Quansah, Y Chen, S Yang, J Wang, D Sun… - Frontiers in …, 2023‏ - frontiersin.org
Malaria caused by Plasmodium is still a serious public health problem. Genomic editing is
essential to understand parasite biology, elucidate mechanical pathways, uncover gene …

[HTML][HTML] Comparative spatial proteomics of Plasmodium-infected erythrocytes

A Siau, JW Ang, O Sheriff, R Hoo, HP Loh, D Tay… - Cell Reports, 2023‏ - cell.com
Plasmodium parasites contribute to one of the highest global infectious disease burdens. To
achieve this success, the parasite has evolved a range of specialized subcellular …

[HTML][HTML] Significance of RNA N6-methyladenosine regulators in the diagnosis and subtype classification of coronary heart disease using the Gene Expression …

Y Jiang, Y Pan, T Long, J Qi, J Liu… - Frontiers in …, 2023‏ - frontiersin.org
Background Many investigations have revealed that alterations in m6A modification levels
may be linked to coronary heart disease (CHD). However, the specific link between m6A …

An update on cerebral malaria for therapeutic intervention

C Panda, RK Mahapatra - Molecular Biology Reports, 2022‏ - Springer
Background Cerebral malaria is often pronounced as a major life-threatening neurological
complication of Plasmodium falciparum infection. The complex pathogenic landscape of the …

Comparative transcriptome database for Camellia sinensis reveals genes related to the cold sensitivity and albino mechanism of 'Anji Baicha'

X Zheng, ZM Ali, PK Lim, M Mutwil… - Physiologia …, 2024‏ - Wiley Online Library
Tea, a globally popular beverage, contains various beneficial secondary metabolites. Tea
plants (Camellia sinensis) exhibit diverse genetic traits across cultivars, impacting yield …

Enhancing Gene Co-Expression Network Inference for the Malaria Parasite Plasmodium falciparum

Q Li, KA Button-Simons, MAC Sievert, E Chahoud… - Genes, 2024‏ - mdpi.com
Background: Malaria results in more than 550,000 deaths each year due to drug resistance
in the most lethal Plasmodium (P.) species P. falciparum. A full P. falciparum genome was …

Dual RNA Sequencing Meta-analysis in Plasmodium Infection Identifies Host-Parasite Interactions

P Mukherjee, G Burgio, E Heitlinger - Msystems, 2021‏ - journals.asm.org
ABSTRACT Dual RNA sequencing (RNA-Seq) is the simultaneous transcriptomic analysis of
interacting symbionts, for example, in malaria. Potential cross-species interactions identified …

[HTML][HTML] Hybrid Deep Learning Based on a Heterogeneous Network Profile for Functional Annotations of Plasmodium falciparum Genes

A Suratanee, K Plaimas - International Journal of Molecular Sciences, 2021‏ - mdpi.com
Functional annotation of unknown function genes reveals unidentified functions that can
enhance our understanding of complex genome communications. A common approach for …

LSTrAP-Crowd: prediction of novel components of bacterial ribosomes with crowd-sourced analysis of RNA sequencing data

B Hew, QW Tan, W Goh, JWX Ng, M Mutwil - BMC biology, 2020‏ - Springer
Background Bacterial resistance to antibiotics is a growing health problem that is projected
to cause more deaths than cancer by 2050. Consequently, novel antibiotics are urgently …

LSTrAP-Kingdom: an automated pipeline to generate annotated gene expression atlases for kingdoms of life

W Goh, M Mutwil - Bioinformatics, 2021‏ - academic.oup.com
Motivation There are now more than two million RNA sequencing experiments for plants,
animals, bacteria and fungi publicly available, allowing us to study gene expression within …