Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions
RS McIntyre, DS Cha, JK Soczynska… - Depression and …, 2013 - Wiley Online Library
Background Few reports have aimed to describe the mediational effect of cognitive deficits
on functional outcomes in major depressive disorder (MDD), and relatively few interventions …
on functional outcomes in major depressive disorder (MDD), and relatively few interventions …
Cognitive functioning in the first-episode of major depressive disorder: A systematic review and meta-analysis.
Objective: Cognitive deficits are frequently observed in major depression. Yet, when these
deficits emerge and how they relate to the depressed state is unclear. The aim of this 2-part …
deficits emerge and how they relate to the depressed state is unclear. The aim of this 2-part …
Recognition and treatment of cognitive dysfunction in major depressive disorder
H Zuckerman, Z Pan, C Park, E Brietzke… - Frontiers in …, 2018 - frontiersin.org
Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …
Cognitive dysfunction in unipolar depression: implications for treatment
Objective The primary objective of this review is to examine the literature assessing
abnormalities in neural circuitry and cognition early in the course of major depressive …
abnormalities in neural circuitry and cognition early in the course of major depressive …
Integrating new findings and examining clinical applications of pattern separation
Pattern separation, the ability to independently represent and store similar experiences, is a
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
Cognitive remission: a novel objective for the treatment of major depression?
Background Cognitive dysfunction in major depressive disorder (MDD) encompasses
several domains, including but not limited to executive function, verbal memory, and …
several domains, including but not limited to executive function, verbal memory, and …
Cognitive training for impaired neural systems in neuropsychiatric illness
S Vinogradov, M Fisher… - …, 2012 - nature.com
Neuropsychiatric illnesses are associated with dysfunction in distributed prefrontal neural
systems that underlie perception, cognition, social interactions, emotion regulation, and …
systems that underlie perception, cognition, social interactions, emotion regulation, and …
Cognitive dysfunction in major depressive disorder: a state-of-the-art clinical review
B Bortolato, A F. Carvalho… - CNS & Neurological …, 2014 - benthamdirect.com
Major depressive disorder (MDD) is a prevalent and recurring mental disorder often
associated with high rates of non-recovery and substantial consequences on psychosocial …
associated with high rates of non-recovery and substantial consequences on psychosocial …
Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …
to functional impairments but are barely addressed in current therapies. Novel treatment …
The prevalence, measurement, and treatment of the cognitive dimension/domain in major depressive disorder
RS McIntyre, HX **ao, K Syeda, M Vinberg… - CNS drugs, 2015 - Springer
Insufficient outcomes amongst adults with major depressive disorder (MDD) provide the
impetus to identify and refine therapeutic targets that are most critical to outcome from …
impetus to identify and refine therapeutic targets that are most critical to outcome from …