The prediction of three-dimensional (3D) protein structure from amino acid sequences has
stood as a significant challenge in computational and structural bioinformatics for decades …

Fusion of plasma membranes is essential for skeletal muscle development, regeneration,
exercise-induced adaptations, and results in a cell that contains hundreds to thousands of …

Muscle cell fusion is a multistep process where the final step of the reaction drives
progression beyond early hemifusion events to complete fusion. This step requires activity of …

Muscle regeneration is essential for vertebrate muscle homeostasis and recovery after
injury. During regeneration, muscle stem cells differentiate into myocytes, which then fuse …

Background Skeletal muscle development and regeneration depend on cellular fusion of
myogenic progenitors to generate multinucleated myofibers. These progenitors utilize two …

The fusion of mononucleated myoblasts produces multinucleated muscle fibers leading to
the formation of skeletal muscle. Myomaker, a skeletal muscle-specific membrane protein, is …

The development and growth of fish skeletal muscles require myoblast fusion to generate
multinucleated myofibers. While zebrafish fast-twitch muscle can fuse to generate …

The evolutionary origins of chordates and their diversification into the three major subphyla
of tunicates, vertebrates, and cephalochordates pose myriad questions about the genetic …

Starch‐binding domain‐containing protein 1 (STBD1) is a glycogen‐binding protein
discovered in skeletal muscle gene differential expression that is pivotal to cellular energy …

Recent advances in the transcriptomics, translatomics, and proteomics have led us to the
exciting new world of functional endogenous microproteins. These microproteins have a …