Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Sex differences in the brain: Implications for behavioral and biomedical research

E Choleris, LAM Galea, F Sohrabji, KM Frick - … & Biobehavioral Reviews, 2018 - Elsevier
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Neuromodulation by oxytocin and vasopressin

R Stoop - Neuron, 2012 - cell.com
Oxytocin (OT) and vasopressin (VP) are two closely related neuropeptides, widely known for
their peripheral hormonal effects. Specific receptors have also been found in the brain …

Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery

Z Song, HE Albers - Frontiers in neuroendocrinology, 2018 - Elsevier
Oxytocin (OT) and arginine-vasopressin (AVP) act in the brain to regulate social
cognition/social behavior and in the periphery to influence a variety of physiological …

Dynamic influences on the neural encoding of social valence

N Padilla-Coreano, KM Tye… - Nature Reviews …, 2022 - nature.com
Social signals can serve as potent emotional triggers with powerful impacts on processes
from cognition to valence processing. How are social signals dynamically and flexibly …

Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior

HE Ross, LJ Young - Frontiers in neuroendocrinology, 2009 - Elsevier
Oxytocin is produced in the hypothalamus and released into the circulation through the
neurohypophyseal system. Peripherally released oxytocin facilitates parturition and milk …

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles

A Verma, O Uzun, Y Hu, Y Hu, HS Han, N Watson… - Nature materials, 2008 - nature.com
Nanoscale objects are typically internalized by cells into membrane-bounded endosomes
and fail to access the cytosolic cell machinery. Whereas some biomacromolecules may …

Remotely triggerable drug delivery systems

BP Timko, T Dvir, DS Kohane - Advanced materials, 2010 - Wiley Online Library
Triggerable drug delivery systems enable on‐demand controlled release profiles that may
enhance therapeutic effectiveness and reduce systemic toxicity. Recently, a number of new …

Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice

M Yoshida, Y Takayanagi, K Inoue, T Kimura… - Journal of …, 2009 - jneurosci.org
The oxytocin receptor has been implicated in the regulation of reproductive physiology as
well as social and emotional behaviors. The neurochemical mechanisms by which oxytocin …