Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The goal of this article is to provide a general review of the epidemiology, acute care, and
chronic management of adult patients with traumatic brain injuries (TBI). This text was …

Background Patients with brain injury who are unresponsive to commands may perform
cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and …

Background and purpose Patients with acquired brain injury and acute or prolonged
disorders of consciousness (DoC) are challenging. Evidence to support diagnostic decisions …

The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Background Brain activation in response to spoken motor commands can be detected by
electroencephalography (EEG) in clinically unresponsive patients. The prevalence and …

Importance Moderate to severe traumatic brain injury (msTBI) is a major cause of death and
disability in the US and worldwide. Few studies have enabled prospective, longitudinal …

The efficacy of amantadine in the symptomatic treatment of patients with Parkinson's
disease, discovered serendipitously more than 50 years ago, has stood the test of time and …

The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …