Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

The non-canonical Wnt/Ca2+ signaling cascade is less characterized than their canonical
counterpart, the Wnt/b-catenin pathway. The non-canonical Wnt signaling pathways are …

The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …

The Wnt signaling pathway plays a role in the development of the central nervous system
and growing evidence indicates that Wnts also regulates the structure and function of the …

Understanding the mechanisms underlying autism spectrum disorders (ASDs) is a
challenging goal. Here we review recent progress on several fronts, including genetics …

Alzheimer's disease (AD) is the most common form of dementia in the older population,
however, the precise cause of the disease is unknown. The neuropathology is characterized …

In the adult brain new neurons are continuously generated mainly in two regions, the
subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) in the …

Wnt signaling function starts during the development of the nervous system and is crucial for
synaptic plasticity in the adult brain. Clearly Wnt effects in synaptic and plastic processes are …

Growing evidence indicates that Wingless-type (Wnt) signaling plays an important role in the
maturation of the central nervous system. We report here that Wingless-type family member …