Synthesis and pharmacological activities of pyrazole derivatives: A review

K Karrouchi, S Radi, Y Ramli, J Taoufik, YN Mabkhot… - Molecules, 2018 - mdpi.com
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

The therapeutic voyage of pyrazole and its analogs: a review

MF Khan, MM Alam, G Verma, W Akhtar… - European journal of …, 2016 - Elsevier
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review

G Yadav, S Ganguly - European journal of medicinal chemistry, 2015 - Elsevier
Benzimidazoles are the fused heterocyclic ring systems which form an integral part of
vitamin B 12 and have been luring many researchers all over the world to assess their …

Comprehensive review in current developments of benzimidazole‐based medicinal chemistry

RS Keri, A Hiremathad, S Budagumpi… - Chemical biology & …, 2015 - Wiley Online Library
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …

Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities

M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …

Design, synthesis and molecular modeling of pyrazole–quinoline–pyridine hybrids as a new class of antimicrobial and anticancer agents

CB Sangani, JA Makawana, X Zhang… - European Journal of …, 2014 - Elsevier
A new series of pyrazole–quinoline–pyridine hybrids were designed based on molecular
hybridization technique and synthesized by a base-catalyzed cyclocondensation reaction …

Functionalized benzimidazole scaffolds: privileged heterocycle for drug design in therapeutic medicine

OO Ajani, DV Aderohunmu, CO Ikpo… - Archiv der …, 2016 - Wiley Online Library
Benzimidazole derivatives are crucial structural scaffolds found in diverse libraries of
biologically active compounds which are therapeutically useful agents in drug discovery and …

Antimicrobial potential of benzimidazole derived molecules

Y Bansal, M Kaur, G Bansal - Mini Reviews in Medicinal …, 2019 - ingentaconnect.com
Structural resemblance of benzimidazole nucleus with purine nucleus in nucleotides makes
benzimidazole derivatives attractive ligands to interact with biopolymers of a living system …

Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review

S Tahlan, S Kumar, B Narasimhan - BMC chemistry, 2019 - Springer
Background Benzimidazole is a heterocyclic moiety whose derivatives are present in many
of the bioactive compounds and posses diverse biological and clinical applications …

Synthesis of azo dyes possessing N-heterocycles and evaluation of their anticancer and antibacterial properties

Z Ghasemi, S Azizi, R Salehi, HS Kafil - Monatshefte für Chemie-Chemical …, 2018 - Springer
Abstract A series of 4-(1-azolyl) aniline derivatives (azole= imidazole, benzimidazole,
pyrazole, 3-methylpyrazole, and 4-methylpyrazole) underwent diazotization reaction by …