Malaria, the most prevalent mosquito-borne infectious disease worldwide, has accompanied
humanity for millennia and remains an important public health issue despite advances in its …

Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …

Antibody-mediated opsonic phagocytosis (OP) of Plasmodium falciparum blood-stage
merozoites has been associated with protection against malaria. However, the precise …

Excessive host immune responses contribute to severe malaria with high mortality. Here, we
show that PRL2 in innate immune cells is highly related to experimental malaria disease …

Malaria is a parasitic disease (caused by different Plasmodium species) that affects millions
of people worldwide. The lack of effective malaria drugs and a vaccine contributes to this …

Newly emerging data suggest that several neutrophil defense mechanisms may play a role
in both aggravating and protecting against malaria. These exciting findings suggest that the …

Background'Benign ethnic neutropenia'(BEN) is a heritable condition characterized by lower
neutrophil counts, predominantly observed in individuals of African ancestry, and the genetic …

Introduction Placental malaria (PM) is characterized by accumulation of inflammatory
leukocytes in the placenta, leading to poor pregnancy outcomes. Understanding of the …

Malaria, caused by infection with Plasmodium parasites, drives multiple regulatory
responses across the immune landscape. These regulatory responses help to protect …

Plasmodium falciparum pathogenesis is complex and intimately connected to vascular
physiology. This is exemplified by cerebral malaria (CM), a neurovascular complication that …