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The importance of antimicrobial resistance in medical mycology
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …
along with significant agricultural crop loss caused by various fungal species, has resulted in …
VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center
B Amos, C Aurrecoechea, M Barba… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB,
https://veupathdb. org) represents the 2019 merger of VectorBase with the EuPathDB …
https://veupathdb. org) represents the 2019 merger of VectorBase with the EuPathDB …
Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR
Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …
but the supramolecular architecture of this carbohydrate-rich composite remains …
Flucytosine and its clinical usage
LSM Sigera, DW Denning - Therapeutic advances in …, 2023 - journals.sagepub.com
Flucytosine is an antifungal agent first licensed in the 1970's. However, its clinical value has
long been overlooked and its availability across the globe is limited. This review highlights …
long been overlooked and its availability across the globe is limited. This review highlights …
Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …
TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …
to present many challenges to their effective management. The repertoire of antifungal drugs …
[HTML][HTML] The consequences of our changing environment on life threatening and debilitating fungal diseases in humans
Human activities have significantly impacted the environment and are changing our climate
in ways that will have major consequences for ourselves, and endanger animal, plant and …
in ways that will have major consequences for ourselves, and endanger animal, plant and …
Aspergillus fumigatus and aspergillosis: from basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
What is new in FungiDB: a web-based bioinformatics platform for omics-scale data analysis for fungal and oomycete species
Abstract FungiDB (https://fungidb. org) serves as a valuable online resource that seamlessly
integrates genomic and related large-scale data for a wide range of fungal and oomycete …
integrates genomic and related large-scale data for a wide range of fungal and oomycete …