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Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex
E Taverna, M Götz, WB Huttner - Annual review of cell and …, 2014 - annualreviews.org
Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …
The outer subventricular zone and primate-specific cortical complexification
Evolutionary expansion and complexification of the primate cerebral cortex are largely
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …
Tumor suppressors BTG1 and BTG2: Beyond growth control
L Yuniati, B Scheijen, LT van der Meer… - Journal of cellular …, 2019 - Wiley Online Library
Since the identification of B‐cell translocation gene 1 (BTG1) and BTG2 as antiproliferation
genes more than two decades ago, their protein products have been implicated in a variety …
genes more than two decades ago, their protein products have been implicated in a variety …
A dynamic unfolded protein response contributes to the control of cortical neurogenesis
The cerebral cortex contains layers of neurons sequentially generated by distinct lineage-
related progenitors. At the onset of corticogenesis, the first-born progenitors are apical …
related progenitors. At the onset of corticogenesis, the first-born progenitors are apical …
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in develo** ferret neocortex
The evolutionary increase in size and complexity of the primate neocortex is thought to
underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene …
underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene …
[HTML][HTML] Expression of human‐specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility
L ** mouse neocortex
The evolutionary expansion of the neocortex in mammals has been linked to enlargement of
the subventricular zone (SVZ) and increased proliferative capacity of basal progenitors …
the subventricular zone (SVZ) and increased proliferative capacity of basal progenitors …