Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

The α, β polyunsaturated lipid aldehydes are potent lipid electrophiles that covalently modify
lipids, proteins, and nucleic acids. Recent work highlights the critical role these lipids play …

Bile acid (BA) has been reported to improve growth performance and play an important role
in lipid metabolism of fish. Five diets were formulated to investigate the effects of dietary bile …

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to
acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal …

The liver is necessary for survival. Its strategic localisation, blood flow and prominent role in
the metabolism of xenobiotics render this organ particularly susceptible to injury by …

Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …

This review on recent research advances of the lipid peroxidation product 4-hydroxy-
nonenal (HNE) has four major topics: I. the formation of HNE in various organs and tissues …

Alcoholic liver disease claims two million lives per year. We previously reported that
autophagy protected against alcohol-induced liver injury and steatosis by removing …

Metastable aldehydes produced by lipid peroxidation act as' toxic second messengers' that
extend the injurious potential of free radicals. 4-hydroxy 2-nonenal (HNE), a highly toxic and …

Damage-associated molecular patterns are signalling molecules involved in inflammatory
responses and restoration of homeostasis. Chronic release of these molecules can also …