Pre-clinical models in implant dentistry: past, present, future

N Blanc-Sylvestre, P Bouchard, C Chaussain, C Bardet - Biomedicines, 2021 - mdpi.com
Biomedical research seeks to generate experimental results for translation to clinical
settings. In order to improve the transition from bench to bedside, researchers must draw …

An Imbalance of the Immune System Instead of a Disease Behind Marginal Bone Loss Around Oral Implants: Position Paper.

T Albrektsson, C Dahlin, D Reinedahl… - … Journal of Oral & …, 2020 - search.ebscohost.com
The purpose of this paper is to present evidence that supports the notion that the primary
reason behind marginal bone loss and implant failure is immune-based and that bacterial …

A biomimetic multifunctional scaffold for infectious vertical bone augmentation

Y Zhang, Z Li, H Guo, Q Wang, B Guo… - Advanced …, 2024 - Wiley Online Library
The regenerative treatment of infectious vertical bone defects remains difficult and
challenging today. Current clinical treatments are limited in their ability to control bacteria …

Is complete re-osseointegration of an infected dental implant possible? histologic results of a dog study: a short communication

M Schlee, L Naili, F Rathe, U Brodbeck… - Journal of clinical …, 2020 - mdpi.com
Complete reosseointegration after treatment of periimplantitis was never published yet. This
short scientific communication reports about results of a randomized controlled preclinical …

Changes in the microcirculation in periodontal tissue due to experimental peri-implantitis

R Yamamoto, K Amano, SW Takahashi, M To… - Journal of oral …, 2021 - Elsevier
Objectives Peri-implantitis causes dislodgement of dental implants due to inflammation in
the peri-implant tissue. The microcirculation in the periodontal tissue undergoes …

Micro computed tomography and immunohistochemistry analysis of dental implant osseointegration in animal experimental model: a sco** review

A Putri, F Pramanik, A Azhari - European Journal of Dentistry, 2023 - thieme-connect.com
Osseointegration is a complex process that involves the interaction of dental implants, bone,
and the immune system. Preclinical testing was carried out to develop a better …

IL-6 Inhibitor Tocilizumab Reduces Bone Resorption Around Implants with Bacterial Infection During Osseointegration: A Pilot Study in Rabbits.

M Zeng, M Xu, L Wang, P Peng… - International Journal of …, 2024 - search.ebscohost.com
Purpose: To evaluate the effect of interleukin-6 (IL-6) inhibitor (tocilizumab) on bacterial
infection-associated bone resorption around implants during osseointegration in rabbits …

Experimental models for peri-implant diseases: a narrative review

D Yin, S Zhan, Y Liu, L Yan, B Shi, X Wang… - Clinical Oral …, 2024 - Springer
Objectives Peri-implant diseases, being the most common implant-related complications,
significantly impact the normal functioning and longevity of implants. Experimental models …

Micro-Computed Tomography Analysis of Peri-Implant Bone Defects Exposed to a Peri-Implantitis Microcosm, with and without Bone Substitute, in a Rabbit Model: A …

C Panes, I Valdivia-Gandur, C Veuthey, V Sousa… - Bioengineering, 2024 - mdpi.com
Peri-implantitis is an inflammatory condition characterized by inflammation in the peri-
implant connective tissue and a progressive loss of supporting bone; it is commonly …

Application of Immediate Implant Placement Techniques in Peri-implantitis Modeling

H Zhang, Y Yuan, X Wu, H Xue, R Yu… - Journal of Craniofacial …, 2023 - journals.lww.com
Objectives: To explore the use of immediate implant placement technique in peri-implantitis
modeling, shorten the modeling period, and obtain similar effects. Materials and Methods …