Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Bone substitutes in orthopaedic surgery: from basic science to clinical practice

V Campana, G Milano, E Pagano, M Barba… - Journal of Materials …, 2014 - Springer
Bone substitutes are being increasingly used in surgery as over two millions bone grafting
procedures are performed worldwide per year. Autografts still represent the gold standard …

Umbilical cord as prospective source for mesenchymal stem cell‐based therapy

I Arutyunyan, A Elchaninov, A Makarov… - Stem cells …, 2016 - Wiley Online Library
The paper presents current evidence on the properties of human umbilical cord‐derived
mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of …

Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti …

JH YlÖstalo, TJ Bartosh, K Coble, DJ Prockop - Stem cells, 2012 - academic.oup.com
Culturing cells in three dimension (3D) provides an insight into their characteristics in vivo.
We previously reported that human mesenchymal stem/stromal cells (hMSCs) cultured as …

Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis

A Bronckaers, P Hilkens, W Martens, P Gervois… - Pharmacology & …, 2014 - Elsevier
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Comparison of the biological characteristics of mesenchymal stem cells derived from the human placenta and umbilical cord

M Wu, R Zhang, Q Zou, Y Chen, M Zhou, X Li, R Ran… - Scientific Reports, 2018 - nature.com
Mesenchymal stem/stromal cells (MSCs) derived from placental tissue show great
therapeutic potential and have been used in medical treatment, but the similarity and …

Current and upcoming therapies for ocular surface chemical injuries

A Baradaran-Rafii, M Eslani, Z Haq, E Shirzadeh… - The ocular …, 2017 - Elsevier
Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular
surface complications. Acute interventions are directed at decreasing the extent of the injury …

Concise review: two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation

DJ Prockop - Stem cells, 2013 - academic.oup.com
Recent data demonstrated that MSCs can be activated by proinflammatory signals to
introduce two negative feedback loops into the generic pathway of inflammation. In one …

Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma

F Braza, S Dirou, V Forest, V Sauzeau, D Hassoun… - Stem …, 2016 - academic.oup.com
Mesenchymal stem cell (MSC) immunosuppressive functions make them attractive
candidates for anti-inflammatory therapy in allergic asthma. However, the mechanisms by …