The role of ketogenic metabolic therapy on the brain in serious mental illness: a review

S Sethi, JM Ford - Journal of psychiatry and brain science, 2022 - pmc.ncbi.nlm.nih.gov
In search of interventions targeting brain dysfunction and underlying cognitive impairment in
schizophrenia, we look at the brain and beyond to the potential role of dysfunctional …

Hippocampal circuit dysfunction in psychosis

S Knight, R McCutcheon, D Dwir, AA Grace… - Translational …, 2022 - nature.com
Despite strong evidence of the neurodevelopmental origins of psychosis, current
pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and …

Brain aging patterns in a large and diverse cohort of 49,482 individuals

Z Yang, J Wen, G Erus, ST Govindarajan, R Melhem… - Nature medicine, 2024 - nature.com
Brain aging process is influenced by various lifestyle, environmental and genetic factors, as
well as by age-related and often coexisting pathologies. Magnetic resonance imaging and …

Brain network localization of gray matter atrophy and neurocognitive and social cognitive dysfunction in schizophrenia

Y Cheng, H Cai, S Liu, Y Yang, S Pan, Y Zhang, F Mo… - Biological …, 2025 - Elsevier
Background Numerous studies have established the presence of gray matter atrophy and
brain activation abnormalities during neurocognitive and social cognitive tasks in …

Syntactic complexity and diversity of spontaneous speech production in schizophrenia spectrum and major depressive disorders

K Schneider, K Leinweber, H Jamalabadi… - Schizophrenia, 2023 - nature.com
Abstract Syntax, the grammatical structure of sentences, is a fundamental aspect of
language. It remains debated whether reduced syntactic complexity is unique to …

High-fat diet consumption promotes adolescent neurobehavioral abnormalities and hippocampal structural alterations via microglial overactivation accompanied by …

X Yao, C Yang, X Jia, Z Yu, C Wang, J Zhao… - Brain, Behavior, and …, 2024 - Elsevier
Mounting evidence suggests that high-fat diet (HFD) consumption increases the risk for
depression, but the neurophysiological mechanisms involved remain to be elucidated. Here …

[HTML][HTML] Postsynaptic proteins at excitatory synapses in the brain—relationship with depressive disorders

S Samojedny, E Czechowska… - International journal of …, 2022 - mdpi.com
Depressive disorders (DDs) are an increasingly common health problem that affects all age
groups. DDs pathogenesis is multifactorial. However, it was proven that stress is one of the …

[HTML][HTML] Altered in vivo early neurogenesis traits in patients with depression: Evidence from neuron-derived extracellular vesicles and electroconvulsive therapy

X **e, S Xu, L Yao, M Chen, H Zhang, C Wang, C Nagy… - Brain Stimulation, 2024 - Elsevier
Background The neurogenesis hypothesis is a promising candidate etiologic hypothesis for
depression, and it is associated with electroconvulsive therapy (ECT). However, human in …

Brain structural associations of syntactic complexity and diversity across schizophrenia spectrum and major depressive disorders, and healthy controls

K Schneider, N Alexander, A Jansen, I Nenadić… - Schizophrenia, 2024 - nature.com
Deviations in syntax production have been well documented in schizophrenia spectrum
disorders (SSD). Recently, we have shown evidence for transdiagnostic subtypes of …

Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental …

M Carrier, CW Hui, V Watters, E Šimončičová… - Brain, Behavior, and …, 2024 - Elsevier
Introduction A wide range of positive, negative, and cognitive symptoms compose the
clinical presentation of schizophrenia. Schizophrenia is a multifactorial disorder in which …