The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

Current research in biology uses evermore complex computational and imaging tools. Here
we describe Icy, a collaborative bioimage informatics platform that combines a community …

The evolution of gene expression in mammalian organ development remains largely
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum …

INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes
us uniquely human. The development of the brain is a highly complex process, and this …

INTRODUCTION Improved understanding of how the develo** human nervous system
differs from that of closely related nonhuman primates is fundamental for teasing out human …

Each language has standard books describing that language's grammatical rules. Biologists
have searched for similar, albeit more complex, principles relating enhancer sequence to …

The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …

Enhancers are distal regulatory elements that can activate tissue-specific gene expression
and are abundant throughout mammalian genomes. Although substantial progress has …

The unique anatomical features of turtles have raised unanswered questions about the
origin of their unique body plan. We generated and analyzed draft genomes of the soft-shell …

Animals are grouped into~ 35 'phyla'based upon the notion of distinct body plans,,,.
Morphological and molecular analyses have revealed that a stage in the middle of …