Sperm cryopreservation: A review on current molecular cryobiology and advanced approaches

M Hezavehei, M Sharafi, HM Kouchesfahani… - Reproductive …, 2018 - Elsevier
The cryopreservation of spermatozoa was introduced in the 1960s as a route to fertility
preservation. Despite the extensive progress that has been made in this field, the biological …

Mitochondria: their role in spermatozoa and in male infertility

M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

Oxidative stress and male fertility: role of antioxidants and inositols

MN De Luca, M Colone, R Gambioli, A Stringaro… - Antioxidants, 2021 - mdpi.com
Infertility is defined as a couple's inability to conceive after at least one year of regular
unprotected intercourse. This condition has become a global health problem affecting …

The role of resveratrol in mammalian reproduction

R Pasquariello, N Verdile, TAL Brevini, F Gandolfi… - Molecules, 2020 - mdpi.com
Resveratrol is one of the most investigated natural polyphenolic compounds and is
contained in more than 70 types of plants and in red wine. The widespread interest in this …

Protective roles of seminal plasma exosomes and microvesicles during human sperm cryopreservation

F Mahdavinezhad, MAS Gilani, R Gharaei… - Reproductive …, 2022 - Elsevier
Research question Do seminal plasma microvesicles and exosomes, as two subtypes of
extracellular vesicles, exert cryoprotective properties in sperm cryopreservation? Design …

The efficacy of antioxidants in sperm parameters and production of reactive oxygen species levels during the freeze‐thaw process: A systematic review and meta …

R Bahmyari, M Zare, R Sharma, A Agarwal… - Andrologia, 2020 - Wiley Online Library
To investigate the impact of antioxidants in sperm parameters and reduction in reactive
oxygen species production during the freeze‐thaw process. PubMed, Scopus, Web of …

Roles of AMP-activated protein kinase (AMPK) in mammalian reproduction

W Yang, L Wang, F Wang, S Yuan - Frontiers in Cell and …, 2020 - frontiersin.org
Reproduction is an energy demanding function and only take place in case of sufficient
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …

AMPK function in mammalian spermatozoa

D Martin-Hidalgo, A Hurtado de Llera… - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase AMPK regulates cellular energy by controlling metabolism
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …

Improving the quality of cryopreserved goat semen with a commercial bull extender supplemented with resveratrol

C Lv, A Larbi, G Wu, Q Hong, G Quan - Animal reproduction science, 2019 - Elsevier
The purpose of the current study was to evaluate the effects of resveratrol (RSV) on the
quality of frozen-thawed goat sperm. Semen samples from four bucks were divided into five …

Human sperm as an in vitro model to assess the efficacy of antioxidant supplements during sperm handling: A narrative review

E Moretti, C Signorini, R Corsaro, M Giamalidi… - Antioxidants, 2023 - mdpi.com
Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due
to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction …