Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity
A Hammarstedt, S Gogg, S Hedjazifar… - Physiological …, 2018 - journals.physiology.org
The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …
However, it has a limited ability to expand by recruiting and/or differentiating available …
Extracellular matrix remodeling of adipose tissue in obesity and metabolic diseases
FJ Ruiz-Ojeda, A Méndez-Gutiérrez… - International journal of …, 2019 - mdpi.com
The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …
controls differentiation, migration, repair, survival, and development, and it seems that its …
Heterogeneity of adipose tissue in development and metabolic function
T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …
compartmentalized into individual depots and distributed throughout the body. These …
Mechanisms of obesity-and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review
R Ruze, J Song, X Yin, Y Chen, R Xu… - Signal transduction and …, 2023 - nature.com
Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …
exponentially since these two diseases were recognized as important risk factors for …
Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system
Obesity and metabolic syndrome (MetS) are global epidemics, driven by an obesogenic
environment. This is mediated by complex underlying pathophysiology, in which chronic …
environment. This is mediated by complex underlying pathophysiology, in which chronic …
Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial
Aims/hypothesis Pancreatic fat accumulation may contribute to the development of beta cell
dysfunction. Exercise training improves whole-body insulin sensitivity, but its effects on …
dysfunction. Exercise training improves whole-body insulin sensitivity, but its effects on …
Fatty pancreas: A possible risk factor for pancreatic cancer in animals and humans
M Takahashi, M Hori, R Ishigamori, M Mutoh… - Cancer …, 2018 - Wiley Online Library
Obesity, type 2 diabetes mellitus (T2 DM) and aging are associated with pancreatic cancer
risk, but the mechanisms of pancreatic cancer development caused by these factors are not …
risk, but the mechanisms of pancreatic cancer development caused by these factors are not …
Microbiota in pancreatic diseases: a review of the literature
T Schepis, SS De Lucia, EC Nista, V Manilla… - Journal of Clinical …, 2021 - mdpi.com
The gut microbiota is a critical element in the balance between human health and disease.
Its impairment, defined as dysbiosis, is associated with gastroenterological and systemic …
Its impairment, defined as dysbiosis, is associated with gastroenterological and systemic …
Fatty infiltration of the pancreas: a systematic concept analysis
MA Mahyoub, M Elhoumed, AH Maqul… - Frontiers in …, 2023 - frontiersin.org
Fatty infiltration of the pancreas (FIP) has been recognized for nearly a century, yet many
aspects of this condition remain unclear. Regular literature reviews on the diagnosis …
aspects of this condition remain unclear. Regular literature reviews on the diagnosis …
Intrapancreatic fat, pancreatitis, and pancreatic cancer
Pancreatic cancer is typically detected at an advanced stage, and is refractory to most forms
of treatment, contributing to poor survival outcomes. The incidence of pancreatic cancer is …
of treatment, contributing to poor survival outcomes. The incidence of pancreatic cancer is …