Significance: Optical imaging using the endogenous fluorescence of metabolic cofactors has
enabled nondestructive examination of dynamic changes in cell and tissue function both in …

Photoluminescent cyclometalated iridium (III) complexes are now a well established class of
organometallic compounds with advantageous potential applications in biology and life …

Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are
susceptible to senescence during aging. We demonstrate the importance of the amount of …

The function of a T cell depends on its subtype and activation state. Here, we show that
imaging of the autofluorescence lifetime signals of quiescent and activated T cells can be …

Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding
microenvironment in both normal physiology and pathological conditions. While MSCs …

Mesenchymal stem cells (MSCs) are progenitors of connective tissues, which have emerged
as important tools for tissue engineering due to their differentiation potential along various …

Mesenchymal stem cells (MSCs) are multipotent cells that show self-renewal, multi-
directional differentiation, and paracrine and immune regulation. As a result of these …

Monitoring subcellular functional and structural changes associated with metabolism is
essential for understanding healthy tissue development and the progression of numerous …

A recent challenge in the field of bioimaging is to image vital, thick, and complex tissues in
real time and in non-invasive mode. Among the different tools available for diagnostics …

Adenosine triphosphate (ATP) is a universal mediator of metabolism and signaling across
unicellular and multicellular species. There is a fundamental interdependence between the …