[HTML][HTML] A systemic review of the role of enterotoxic Bacteroides fragilis in colorectal cancer

N Scott, E Whittle, P Jeraldo, N Chia - Neoplasia, 2022 - Elsevier
Enterotoxigenic Bacteroides fragilis (ETBF) has received significant attention for a possible
association with, or causal role in, colorectal cancer (CRC). The goal of this review was to …

[HTML][HTML] Intestinal inflammation and Parkinson's disease

Y Li, Y Chen, L Jiang, J Zhang, X Tong, D Chen… - Aging and …, 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second most common neurodegenerative disease which
significantly influences the life quality of patients. The protein α-synuclein plays an important …

Ginkgetin improved experimental colitis by inhibiting intestinal epithelial cell apoptosis through EGFR/PI3K/AKT signaling

Z Geng, L Zuo, J Li, L Yin, J Yang, T Duan… - The FASEB …, 2024 - Wiley Online Library
Excessive apoptosis of intestinal epithelial cells leads to intestinal barrier dysfunction, which
is not only one of the pathological features of inflammatory bowel disease (IBD) but also a …

Intestinal organoids: A thriving and powerful tool for investigating dietary nutrients-intestinal homeostasis axis

D Zhang, X Zhou, W Zhou, SW Cui, S Nie - Food Research International, 2023 - Elsevier
Dietary nutrients regulate intestinal homeostasis through a variety of complex mechanisms,
to affect the host health. Nowadays, various models have been used to investigate the …

Involvement of Abnormal P-α-Syn Accumulation and TLR2-Mediated Inflammation of Schwann Cells in Enteric Autonomic Nerve Dysfunction of Parkinson's Disease …

W Jiang, Y Cheng, Y Wang, J Wu, Z Rong, L Sun… - Molecular …, 2023 - Springer
The study was designed to investigate the pathogenesis of gastrointestinal (GI) impairment
in Parkinson's disease (PD). We utilized 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

Vindoline ameliorates intestinal barrier damage in Crohn's disease mice through MAPK signaling pathway

X Zhang, L Zuo, Z Geng, X Song, J Li, S Ge… - The FASEB …, 2022 - Wiley Online Library
Intestinal inflammation and intestinal barrier damage are important pathological changes in
Crohn's disease (CD). Vindoline is a natural monomer with anti‐inflammatory effects. We …

Exploiting unique features of the gut-brain interface to combat gastrointestinal cancer

A Schledwitz, G **e, JP Raufman - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The gastrointestinal tract comprises a complex ecosystem with extensive opportunities for
functional interactions between neoplastic epithelial cells and stromal, immune, neuronal …

[HTML][HTML] Organoids in recapitulating tumorigenesis driven by risk factors: Current trends and future perspectives

J Zhang, L Wang, Q Song, M **ao, J Gao… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Environmental and exogenous/endogenous factors, in a setting of individual genetic
predisposition, contribute to the cancer development. Over the years, epidemical evidence …

Midgut microbiota affects the intestinal barrier by producing short-chain fatty acids in Apostichopus japonicus

M Song, Z Zhang, Y Li, Y **ang, C Li - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction The intestinal microbiota participates in host physiology and pathology through
metabolites, in which short-chain fatty acids (SCFAs) are considered principal products and …

How ceramides affect the development of colon cancer: from normal colon to carcinoma

N Merz, JC Hartel, S Grösch - Pflügers Archiv-European Journal of …, 2024 - Springer
The integrity of the colon and the development of colon cancer depend on the sphingolipid
balance in colon epithelial cells. In this review, we summarize the current knowledge on how …