Simple Summary Osteosarcoma (OS) is the most common bone tumor in the pediatric
population. Currently, no effective molecularly targeted therapies are available for OS. The …

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents.
It is characterized by a rapid progression, poor prognosis, and early pulmonary metastasis …

The coordinated migration of invasive tumor cells is a complex and dynamic mechanism
driven by diverse cellular and molecular events. Unfortunately, the inherent heterogeneity …

Extracellular acidosis stemming from altered tumor metabolism promotes cancer
progression by enabling tumor cell adaptation to the hostile microenvironment. In …

The management of osteosarcoma (OS) patients presents a significant clinical challenge.
Despite progress in conventional and targeted therapies, the survival rate of OS patients …

Simple Summary Myxofibrosarcoma (MFS) is one of the most common malignant soft tissue
sarcomas. MFS occurs mostly in the extremities of patients after the fifth decade of life as a …

Abstract Background and Objective Radiomics is a field of quantitative imaging involving the
extraction of features from medical images transforming them into mineable data for …

The tumor microenvironment (TME) is integral to cancer progression, impacting metastasis
and treatment response. It consists of diverse cell types, extracellular matrix components …

The type of experimental model for the in vitro testing of drug formulations efficiency
represents an important tool in cancer biology, with great attention being granted to three …

The advancement of personalized treatments in oncology has garnered increasing attention,
particularly for rare and aggressive cancer with low survival rates like the bone tumors …