Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies

KAA Andersen, R Carhart‐Harris… - Acta Psychiatrica …, 2021‏ - Wiley Online Library
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

[HTML][HTML] The cingulum bundle: Anatomy, function, and dysfunction

EJ Bubb, C Metzler-Baddeley, JP Aggleton - … & Biobehavioral Reviews, 2018‏ - Elsevier
The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …

Reduced default mode network functional connectivity in patients with recurrent major depressive disorder

CG Yan, X Chen, L Li, FX Castellanos, TJ Bai… - Proceedings of the …, 2019‏ - pnas.org
Major depressive disorder (MDD) is common and disabling, but its neuropathophysiology
remains unclear. Most studies of functional brain networks in MDD have had limited …

[HTML][HTML] Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

RL Carhart-Harris, L Roseman, M Bolstridge… - Scientific reports, 2017‏ - nature.com
Psilocybin with psychological support is showing promise as a treatment model in psychiatry
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …

Functional connectomics in depression: insights into therapies

Y Chai, YI Sheline, DJ Oathes, NL Balderston… - Trends in cognitive …, 2023‏ - cell.com
Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has …

Large-scale network dysfunction in major depressive disorder: a meta-analysis of resting-state functional connectivity

RH Kaiser, JR Andrews-Hanna, TD Wager… - JAMA …, 2015‏ - jamanetwork.com
Importance Major depressive disorder (MDD) has been linked to imbalanced
communication among large-scale brain networks, as reflected by abnormal resting-state …

Precision psychiatry: a neural circuit taxonomy for depression and anxiety

LM Williams - The Lancet Psychiatry, 2016‏ - thelancet.com
Although there have been tremendous advances in the understanding of human
dysfunctions in the brain circuitry for self-reflection, emotion, and cognitive control, a brain …

Resting-state functional connectivity in major depressive disorder: a review

PC Mulders, PF van Eijndhoven, AH Schene… - Neuroscience & …, 2015‏ - Elsevier
Major depressive disorder (MDD) affects multiple large-scale functional networks in the
brain, which has initiated a large number of studies on resting-state functional connectivity in …

Depressive rumination, the default-mode network, and the dark matter of clinical neuroscience

JP Hamilton, M Farmer, P Fogelman, IH Gotlib - Biological psychiatry, 2015‏ - Elsevier
The intuitive association between self-focused rumination in major depressive disorder
(MDD) and the self-referential operations performed by the brain's default-mode network …

How inflammation affects the brain in depression: a review of functional and structural MRI studies

KM Han, BJ Ham - Journal of clinical neurology (Seoul, Korea), 2021‏ - pmc.ncbi.nlm.nih.gov
This narrative review discusses how peripheral and central inflammation processes affect
brain function and structure in depression, and reports on recent peripheral inflammatory …