[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

Genetic and epigenetic etiology underlying autism spectrum disorder

SH Yoon, J Choi, WJ Lee, JT Do - Journal of clinical medicine, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized
by difficulties in social interaction, language development delays, repeated body …

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice

SS Moy, JJ Nadler, A Perez, RP Barbaro… - Genes, Brain and …, 2004 - Wiley Online Library
Deficits in social interaction are important early markers for autism and related
neurodevelopmental disorders with strong genetic components. Standardized behavioral …

Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder

G Dawson - Development and psychopathology, 2008 - cambridge.org
Advances in the fields of cognitive and affective developmental neuroscience,
developmental psychopathology, neurobiology, genetics, and applied behavior analysis …

The genetics of autism

R Muhle, SV Trentacoste, I Rapin - Pediatrics, 2004 - publications.aap.org
Autism is a complex, behaviorally defined, static disorder of the immature brain that is of
great concern to the practicing pediatrician because of an astonishing 556% reported …

Autism and pervasive developmental disorders

FR Volkmar, C Lord, A Bailey… - Journal of child …, 2004 - Wiley Online Library
The quantity and quality of research into autism and related conditions have increased
dramatically in recent years. Consequently we selectively review key accomplishments and …

The genetics of autistic disorders and its clinical relevance: a review of the literature

CM Freitag - Molecular psychiatry, 2007 - nature.com
Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the
narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially …

Mouse behavioral assays relevant to the symptoms of autism

JN Crawley - Brain pathology, 2007 - Wiley Online Library
While the cause of autism remains unknown, the high concordance between monozygotic
twins supports a strong genetic component. The importance of genetic factors in autism …

Designing mouse behavioral tasks relevant to autistic‐like behaviors

JN Crawley - Mental retardation and developmental disabilities …, 2004 - Wiley Online Library
The importance of genetic factors in autism has prompted the development of mutant mouse
models to advance our understanding of biological mechanisms underlying autistic …

Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum …

DF MacFabe, DP Cain, K Rodriguez-Capote… - Behavioural brain …, 2007 - Elsevier
Clinical observations suggest that certain gut and dietary factors may transiently worsen
symptoms in autism spectrum disorders (ASD), epilepsy and some inheritable metabolic …