Fluid shear stress sensing by the endothelial layer
E Roux, P Bougaran, P Dufourcq… - Frontiers in physiology, 2020 - frontiersin.org
Blood flow produces mechanical frictional forces, parallel to the blood flow exerted on the
endothelial wall of the vessel, the so-called wall shear stress (WSS). WSS sensing is …
endothelial wall of the vessel, the so-called wall shear stress (WSS). WSS sensing is …
A computational fluid dynamics modelling of maternal-fetal heat exchange and blood flow in the umbilical cord
Human fetal thermoregulation, maternal-fetal heat exchange, and the role of the umbilical
cord in these processes are not well understood. Ethical and technical limitations have …
cord in these processes are not well understood. Ethical and technical limitations have …
Analysis of flow-induced transcriptional response and cell alignment of different sources of endothelial cells used in vascular tissue engineering
DM Rojas-González, A Babendreyer, A Ludwig… - Scientific Reports, 2023 - nature.com
Endothelialization of tissue-engineered vascular grafts has proven crucial for implant
functionality and thus clinical outcome, however, the choice of endothelial cells (ECs) is …
functionality and thus clinical outcome, however, the choice of endothelial cells (ECs) is …
Nanoparticle localization in blood vessels: dependence on fluid shear stress, flow disturbances, and flow-induced changes in endothelial physiology
Nanoparticles in the bloodstream are subjected to complex fluid forces as they move
through the curves and branches of healthy or tumor vasculature. While nanoparticles are …
through the curves and branches of healthy or tumor vasculature. While nanoparticles are …
Sinus hemodynamics variation with tilted transcatheter aortic valve deployments
Leaflet thrombosis is a complication associated with transcatheter aortic valve (TAV)
replacement (TAVR) correlated with sinus flow stasis. Sinus hemodynamics are important …
replacement (TAVR) correlated with sinus flow stasis. Sinus hemodynamics are important …
EndOxy: dynamic long-term evaluation of endothelialized gas exchange membranes for a biohybrid lung
S Klein, F Hesselmann, S Djeljadini, T Berger… - Annals of Biomedical …, 2020 - Springer
In the concept of a biohybrid lung, endothelial cells seeded on gas exchange membranes
form a non-thrombogenic an anti-inflammatory surface to overcome the lacking …
form a non-thrombogenic an anti-inflammatory surface to overcome the lacking …
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC
X Zhang, J Sun, P Zhang, T Wen, R Wang… - … Therapy-Nucleic Acids, 2023 - cell.com
During vascular development, endothelial cells (ECs) undergo arterialization in response to
genetic programs and shear stress-triggered mechanotransduction, forming a stable …
genetic programs and shear stress-triggered mechanotransduction, forming a stable …
[HTML][HTML] Advances in human placental biomechanics
RP Mayo - Computational and structural biotechnology journal, 2018 - Elsevier
Pregnancy complications are a major clinical concern due to the related maternal and fetal
morbidity. Many are caused through defective placentation, but research into placental …
morbidity. Many are caused through defective placentation, but research into placental …
Sinus hemodynamics in representative stenotic native bicuspid and tricuspid aortic valves: an in-vitro study
(1) The study's objective is to assess sinus hemodynamics differences between stenotic
native bicuspid aortic valve (BAV) and native tricuspid aortic valve (TrAV) sinuses in order to …
native bicuspid aortic valve (BAV) and native tricuspid aortic valve (TrAV) sinuses in order to …
Human fetal hearts with tetralogy of Fallot have altered fluid dynamics and forces
Studies have suggested the effect of blood flow forces in pathogenesis and progression of
some congenital heart malformations. It is therefore of interest to study the fluid mechanic …
some congenital heart malformations. It is therefore of interest to study the fluid mechanic …