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The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis
Background Ageing is one of the principal risk factors for many chronic diseases. However,
there is considerable between-person variation in the rate of ageing and individual …
there is considerable between-person variation in the rate of ageing and individual …
DNA methylation in lung cancer: mechanisms and associations with histological subtypes, molecular alterations, and major epidemiological factors
PH Hoang, MT Landi - Cancers, 2022 - mdpi.com
Simple Summary Aberrant DNA methylation is associated with multiple malignancies,
including lung cancer. Differences in methylation patterns have been observed across lung …
including lung cancer. Differences in methylation patterns have been observed across lung …
A biosocial return to race? A cautionary view for the postgenomic era
Recent studies demonstrating epigenetic and developmental sensitivity to early
environments, as exemplified by fields like the Developmental Origins of Health and …
environments, as exemplified by fields like the Developmental Origins of Health and …
Ten years of EWAS
S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …
variation in complex diseases for a decade, and epigenome as a research target has …
The association of cigarette smoking with DNA methylation and gene expression in human tissue samples
Cigarette smoking adversely affects many aspects of human health, and epigenetic
responses to smoking may reflect mechanisms that mediate or defend against these effects …
responses to smoking may reflect mechanisms that mediate or defend against these effects …
Per-and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters
Background: Per-and polyfluoroalkyl substances (PFASs) are persistent chemicals that
firefighters encounter. Epigenetic modifications, including DNA methylation, could serve as …
firefighters encounter. Epigenetic modifications, including DNA methylation, could serve as …
Mediation by placental DNA methylation of the association of prenatal maternal smoking and birth weight
Prenatal maternal smoking is a risk factor for lower birth weight. We performed epigenome-
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …
Epigenome-wide association study of depression symptomatology in elderly monozygotic twins
Depression is a severe and debilitating mental disorder diagnosed by evaluation of
affective, cognitive and physical depression symptoms. Severity of these symptoms strongly …
affective, cognitive and physical depression symptoms. Severity of these symptoms strongly …
Accurate ethnicity prediction from placental DNA methylation data
Background The influence of genetics on variation in DNA methylation (DNAme) is well
documented. Yet confounding from population stratification is often unaccounted for in …
documented. Yet confounding from population stratification is often unaccounted for in …
FOXK2 transcription factor and its emerging roles in cancer
Forkhead box (FOX) transcription factors compose a large family of regulators of key
biological processes within a cell. FOXK2 is a member of FOX family, whose biological …
biological processes within a cell. FOXK2 is a member of FOX family, whose biological …