Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

Traditionally, lymphocytic interferon γ (IFN-γ) was considered to be a simple'booster'of
proinflammatory responses by microglia (brain-resident macrophages) during bacterial or …

Interferons (IFNs) are among the first vertebrate immune pathways activated upon viral
infection and are crucial for control of viral replication and dissemination, especially at …

The IFN‐γ/STAT1 immune signaling pathway impacts many homeostatic and pathological
aspects of neurons, beyond its canonical role in controlling intracellular pathogens. Well …

Interferon-gamma (IFNG) is a pleiotropic cytokine that modulates both innate and adaptive
immune networks; it is the most potent activator of macrophages and a signature cytokine of …

The interferon (IFN) system is one of the first lines of defense activated against invading viral
pathogens. Upon secretion, IFNs activate a signaling cascade resulting in the production of …

Pseudorabies virus (PRV) is an alphaherpesvirus related to varicella-zoster virus (VZV) and
herpes simplex virus type 1 (HSV1). PRV is the causative agent of Aujeskzy's disease in …

Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) produce lifelong infections
and are highly prevalent in the human population. Both viruses elicit numerous clinical …

In the last decades, the interest in seaweed has significantly increased. Bioactive
compounds from seaweed's currently receive major attention from pharmaceutical …

Innate immune responses can impact different stages of viral life cycles. Herpes simplex
virus latent infection of neurons and subsequent reactivation provide a unique context for …