Over the last years, the metabolic role of PRL has emerged. PRL excess is known to
promote weight gain, obesity, metabolic syndrome, and impairment in gluco-insulinemic and …

The hypothalamic control of prolactin secretion is different from other anterior pituitary
hormones, in that it is predominantly inhibitory, by means of dopamine from the …

Prolactinomas account for approximately 40% of all pituitary adenomas and are an
important cause of hypogonadism and infertility. The ultimate goal of therapy for …

Obesity and metabolic syndrome, with increased risk of eventual cardiovascular disease
and type II diabetes, are significant problems for patients receiving antipsychotic drugs and …

Abstract Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …

New information about the effects of prolactin (PRL) on metabolic processes warrants re-
evaluation of the overall metabolic actions of PRL. PRL affects metabolic homeostasis by …

Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology.
Recent studies highlight its role in neurohormonal appetite regulation and metabolism …

The discovery of the adipocyte-produced hormone leptin has greatly changed the field of
obesity research and our understanding of energy homeostasis. It is now accepted that …

Background Gender differences in tumor size are supposed to exist in hyperprolactinemia
since microadenomas are more commonly found in women and macroadenomas in men …

Prolactin is pleotropic in nature affecting multiple tissues throughout the body. As a
consequence of the broad range of functions, regulation of anterior pituitary prolactin …