Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Pathogenic microorganisms have to face hostile environments while colonizing and
infecting their hosts. Unfortunately, they can cope with it and have evolved a number of …

Pseudomonas aeruginosa, a Gram‐negative environmental species and an opportunistic
microorganism, establishes itself in vulnerable patients, such as those with cystic fibrosis or …

The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …

Membrane-spanning signaling pathways enable bacteria to alter gene expression in
response to extracytoplasmic stimuli. Many such pathways are cell-surface signaling (CSS) …

Archaeological dental calculus, or mineralized plaque, is a key tool to track the evolution of
oral microbiota across time in response to processes that impacted our culture and biology …

The amenability of the zebrafish to in vivo imaging and genetic analysis has fueled
expanded use of this vertebrate model to investigate the molecular and cellular foundations …

Sigma factors are essential global regulators of transcription initiation in bacteria which
confer promoter recognition specificity to the RNA polymerase core enzyme. They provide …

Neutrophils are highly motile phagocytic cells that play a critical role in the immune
response to infection. Zebrafish (Danio rerio) are increasingly used to study neutrophil …

Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic
resistance in many bacterial pathogens, representing candidate targets for the development …