Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …

Advanced in vitro kidney models are of great importance to the study of renal physiology and
disease. Kidney tubuloids can be established from primary cells derived from adult kidney …

Several functions of autophagy associated with proliferation, differentiation, and migration of
endothelial cells have been reported. Due to lack of models recapitulating angiogenic …

Microfluidic organ-on-a-chip technologies have enabled construction of biomimetic
physiologically and pathologically relevant models. This paper describes an injection …

Inflammatory diseases are often characterised by excessive neutrophil infiltration from the
blood stream to the site of inflammation, which damages healthy tissue and prevents …

Endothelial cells (ECs) are widely used as donor cells in tissue engineering, organoid
vascularization, and in vitro microvascular model development. ECs are invaluable tools for …

Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …

Human induced pluripotent stem cell (hiPSC)-derived brain spheroids can recapitulate the
complex cytoarchitecture of the brain, as well as the genetic/epigenetic footprint of human …

The lymphatic system is essential in maintaining tissue fluid homeostasis as well as antigen
and immune cell transport to lymph nodes. Moreover, lymphatic vasculature plays an …

Despite significant advancements in three-dimensional (3D) cell culture technology and the
acquisition of extensive data, there is an ongoing need for more effective and dependable …