Congenital stationary night blindness (CSNB) refers to a group of genetically and clinically
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …

Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that regulate the cellular levels
of the second messengers, cAMP and cGMP, by controlling their rates of degradation. There …

Due to improved phenoty** and genetic characterization, the field of 'incurable'and
'blinding'inherited retinal diseases (IRDs) has moved substantially forward. Decades of …

During the last two to three decades, a large body of work has revealed the molecular basis
of many human disorders, including retinal and vitreoretinal degenerations and …

Achondroplasia(ACH) is the most common genetic form of dwarfism. This disorder is
inherited as an autosomal dominant trait, although the majority of cases are sporadic. A …

Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that have the unique function of
terminating cyclic nucleotide signaling by catalyzing the hydrolysis of cAMP and GMP. They …

In the last few years there has been a veritable explosion of knowledge about cyclic
nucleotide phosphodiesterases. In particular, the accumulating data showing that there are …

Retinal neurodegeneration associated with the dysfunction or death of photoreceptors is a
major cause of incurable vision loss. Tremendous progress has been made over the last two …

Recent advances have substantially increased the number of genes that are statistically
associated with complex genetic disorders of the CNS such as autism and schizophrenia. It …

Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the
forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic …