Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus

A Kautzky-Willer, J Harreiter, G Pacini - Endocrine reviews, 2016 - academic.oup.com
The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement

A Bhargava, AP Arnold, DA Bangasser… - Endocrine …, 2021 - academic.oup.com
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …

Body roundness index and all-cause mortality among US adults

X Zhang, N Ma, Q Lin, K Chen, F Zheng, J Wu… - JAMA Network …, 2024 - jamanetwork.com
Importance Obesity, especially visceral obesity, is an established risk factor associated with
all-cause mortality. However, the inadequacy of conventional anthropometric measures in …

Obesity in Mexico, prevalence and trends in adults. Ensanut 2018-19

S Barquera, L Hernández-Barrera… - Salud publica de …, 2020 - medigraphic.com
Objective. To describe the prevalence of obesity in Mexican adults stratifying by physical
and sociodemographic conditions and to analyze trends. Materials and methods. The data …

The association of obesity and cardiometabolic traits with incident HFpEF and HFrEF

N Savji, WC Meijers, TM Bartz, V Bhambhani… - JACC: Heart Failure, 2018 - jacc.org
Objectives: This study evaluated the associations of obesity and cardiometabolic traits with
incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF) …

[HTML][HTML] Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia

M Oya, Y Miyasaka, Y Nakamura, M Tanaka… - Cell Metabolism, 2024 - cell.com
Obesity is often associated with aging. However, the mechanism of age-related obesity is
unknown. The melanocortin-4 receptor (MC4R) mediates leptin-melanocortin anti-obesity …

Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure

JR Speakman, JMA de Jong, S Sinha… - Nature …, 2023 - nature.com
Obesity is caused by a prolonged positive energy balance,. Whether reduced energy
expenditure stemming from reduced activity levels contributes is debated,. Here we show …

Association between male sex and outcomes of Coronavirus Disease 2019 (Covid-19)—a Danish nationwide, register-based study

K Kragholm, MP Andersen, TA Gerds… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background and Objectives Male sex has been associated with severe coronavirus
disease 2019 (COVID-19) infection. We examined the association between male sex and …

The prevalence of food addiction as assessed by the Yale Food Addiction Scale: a systematic review

KM Pursey, P Stanwell, AN Gearhardt, CE Collins… - Nutrients, 2014 - mdpi.com
Obesity is a global issue and it has been suggested that an addiction to certain foods could
be a factor contributing to overeating and subsequent obesity. Only one tool, the Yale Food …

Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality

KA Britton, JM Massaro, JM Murabito, BE Kreger… - Journal of the American …, 2013 - jacc.org
Objectives: The aim of this study was to determine whether ectopic fat depots are
prospectively associated with cardiovascular disease, cancer, and all-cause mortality …