[HTML][HTML] Natural compounds and products from an anti-aging perspective

G Bjørklund, M Shanaida, R Lysiuk, M Butnariu… - Molecules, 2022 - mdpi.com
Aging is a very complex process that is accompanied by a degenerative impairment in many
of the major functions of the human body over time. This inevitable process is influenced by …

Functional and structural benefits induced by omega-3 polyunsaturated fatty acids during aging

D Cutuli - Current neuropharmacology, 2017 - benthamdirect.com
Background: Omega-3 polyunsaturated fatty acids (n-3 PUFA) are structural components of
the brain and are indispensable for neuronal membrane synthesis. Along with decline in …

[HTML][HTML] Omega-3 fatty acid rescues ischaemia/perfusion-induced testicular and sperm damage via modulation of lactate transport and xanthine oxidase/uric acid …

RE Akhigbe, MA Hamed, AF Odetayo… - Biomedicine & …, 2021 - Elsevier
This study aimed to explore the potential antioxidant, anti-inflammatory, and anti-apoptotic
effects of omega 3 fatty acid (Ω-3) in a rat model of testicular torsion/detorsion (T/D). Under …

Pharmacological inhibition of ERK signaling rescues pathophysiology and behavioral phenotype associated with 16p11. 2 chromosomal deletion in mice

J Pucilowska, J Vithayathil, M Pagani, C Kelly… - Journal of …, 2018 - jneurosci.org
The human 16p11. 2 microdeletion is one of the most common gene copy number variations
linked to autism, but the pathophysiology associated with this chromosomal abnormality is …

Dietary fatty acids and risk for Alzheimer's disease, dementia, and mild cognitive impairment: a prospective cohort meta-analysis

R Zhu, M Chen, Z Zhang, T Wu, WH Zhao - Nutrition, 2021 - Elsevier
The association between dietary fatty acid intake and Alzheimer's disease (AD), dementia,
and mild cognitive impairment (MCI) risk is inconsistent. This meta-analysis examined the …

Dietary fat intake and risk of Alzheimer's disease and dementia: a meta-analysis of cohort studies

Y Ruan, J Tang, X Guo, K Li, D Li - Current Alzheimer Research, 2018 - benthamdirect.com
Background: Epidemiological studies showed that dietary fat intake is associated with
Alzheimer's disease (AD) and dementia risk, however, the association remain inconsistent …

Walnut oil prevents scopolamine-induced memory dysfunction in a mouse model

J Liao, Y Nai, L Feng, Y Chen, M Li, H Xu - Molecules, 2020 - mdpi.com
For thousands of years, it has been widely believed that walnut is a kind of nut that has
benefits for the human body. Walnut oil, accounting for about 70% of walnut, mainly consists …

Biochemical deficits and cognitive decline in brain aging: Intervention by dietary supplements

J Poddar, M Pradhan, G Ganguly… - Journal of chemical …, 2019 - Elsevier
The aging of brain in the absence of neurodegenerative diseases, usually called non-
pathological brain aging or normal cognitive aging, is characterized by an impairment of …

The role of physical exercise and omega-3 fatty acids in depressive illness in the elderly

S Farioli-Vecchioli, S Sacchetti… - Current …, 2018 - ingentaconnect.com
Background: In adulthood, depression is the most common type of mental illness and will be
the second leading cause of disease by 2020. Major depression dramatically affects the …

Microglia and modifiable life factors: potential contributions to cognitive resilience in aging

MR Duggan, V Parikh - Behavioural brain research, 2021 - Elsevier
Given the increasing prevalence of age-related cognitive decline, it is relevant to consider
the factors and mechanisms that might facilitate an individual's resiliency to such deficits …