Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …

Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from
anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag …

NLRP3 inflammasome can be widely found in epithelial cells and immune cells. The NOD-
like receptors (NLRs) family member NLRP3 contains a central nucleotide-binding and …

Initially described as an interferon (IFN) γ‐inducing factor, interleukin (IL)‐18 is indeed
involved in Th1 and NK cell activation, but also in Th2, IL‐17‐producing γδ T cells and …

Even though the pathogenesis of IBD is complicated, several studies have demonstrated
that excessive interleukin (IL)-17 production is involved in the progression of IBD. 3 …

IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Cytokines have a crucial role in the pathogenesis of inflammatory bowel diseases (IBDs),
such as Crohn's disease and ulcerative colitis, where they control multiple aspects of the …

Inflammatory bowel disease (IBD) is considered a chronic inflammatory and multifactorial
disease of the gastrointestinal tract. Crohn's disease (CD) and ulcerative colitis (UC) are two …