Caveolae are a highly abundant but enigmatic feature of mammalian cells. They form
remarkably stable membrane domains at the plasma membrane but can also function as …

The physiological importance of cholesterol in the cell plasma membrane has attracted
increased attention in recent years. Consequently, the use of methods of controlled …

Lipid rafts are subdomains of the plasma membrane that contain high concentrations of
cholesterol and glycosphingolipids. They exist as distinct liquid-ordered regions of the …

Lipid rafts are specialized structures on the plasma membrane that have an altered lipid
composition as well as links to the cytoskeleton. It has been proposed that these structures …

Increasing evidence suggests that biological membranes can be laterally subdivided into
domains enriched in specific lipid and protein components and that these domains may be …

Protein N-myristoylation refers to the covalent attachment of myristate, a 14-carbon saturated
fatty acid, to the N-terminal glycine of eukaryotic and viral proteins. N-Myristoylproteins have …

Lipid rafts are membrane microdomains that are enriched in cholesterol and
glycosphingolipids. They have been implicated in processes as diverse as signal …

Mechanical stresses modulate cell function by either activating or tuning signal transduction
pathways. Mechanotransduction, the process by which cells convert mechanical stimuli into …

Caveolae, a subset of membrane (lipid) rafts, are flask-like invaginations of the plasma
membrane that contain caveolin proteins, which serve as organizing centers for cellular …

Caveolae are 50-to 100-nm cell-surface plasma membrane invaginations observed in
terminally differentiated cells. They are particularly abundant in endothelial cells, where they …