Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …

The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the
diagnostic workup, outcome, and management. The recommendations are based on …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

The link between dysregulated serotonergic activity and depression and anxiety disorders is
well established, yet the molecular mechanisms underlying these psychopathologies are not …

DNA methylation likely plays a role in the regulation of human stress reactivity. Here we
show that in a genome-wide analysis of blood DNA methylation in 85 healthy individuals, a …

Takotsubo syndrome (TTS) accounts for between 1 and 4% of cases presenting clinically as
an acute coronary syndrome. It typically presents as a transient cardiac phenotype of left …

Aims Takotsubo cardiomyopathy (TTC) remains a potentially life-threatening disease, which
is clinically indistinguishable from acute myocardial infarction (MI). Today, no established …

The serotonergic system and in particular serotonin 1A receptor (5-HT1AR) are implicated in
major depressive disorder (MDD). Here we demonstrated that 5-HT1AR is palmitoylated in …

MicroRNAs (miRNAs) are potent modulators of protein expression that play key roles in
brain pathways regulating neurogenesis and synaptic plasticity. These small RNAs may be …