The expanding role of pyridine and dihydropyridine scaffolds in drug design
Y Ling, ZY Hao, D Liang, CL Zhang… - Drug design …, 2021 - Taylor & Francis
Pyridine-based ring systems are one of the most extensively used heterocycles in the field of
drug design, primarily due to their profound effect on pharmacological activity, which has led …
drug design, primarily due to their profound effect on pharmacological activity, which has led …
Deep eutectic solvents (DESs) as eco-friendly and sustainable solvent/catalyst systems in organic transformations
S Khandelwal, YK Tailor, M Kumar - Journal of Molecular Liquids, 2016 - Elsevier
The development of efficient and environmentally benign synthetic protocols has attracted
increasing interest in modern organic syntheses in view of the growing concern over the …
increasing interest in modern organic syntheses in view of the growing concern over the …
1, 4-Dihydropyridine: Synthetic advances, medicinal and insecticidal properties
1, 4-Dihydropyridine (1, 4-DHP) is one of the foremost notable organic scaffolds with diverse
pharmaceutical applications. This study will highlight recent accomplishments in the …
pharmaceutical applications. This study will highlight recent accomplishments in the …
[HTML][HTML] Novel polyhydroquinoline-hydrazide-linked Schiff's base derivatives: multistep synthesis, antimicrobial, and calcium-channel-blocking activities
Polyhydroquinoline (PHQ) are the unsymmetrical Hantzsch derivatives of 1, 4-
dihydropyridines with several biological applications. In this work, twenty-five (3–27) new …
dihydropyridines with several biological applications. In this work, twenty-five (3–27) new …
[ספר][B] Privileged structures in drug discovery: medicinal chemistry and synthesis
L Yet - 2018 - books.google.com
A comprehensive guide to privileged structures and their application in the discovery of new
drugs The use of privileged structures is a viable strategy in the discovery of new medicines …
drugs The use of privileged structures is a viable strategy in the discovery of new medicines …
Synthesis and cytotoxicity evaluation of novel 1, 8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agents
In this study, we aimed to develop hybrid antitumor compounds by synthesizing and
characterizing novel N-substituted acrididine-1, 8-dione derivatives, designed as hybrids of …
characterizing novel N-substituted acrididine-1, 8-dione derivatives, designed as hybrids of …
Magnesium-catalyzed hydroboration of pyridines
Reaction of catalytic quantities of a β-diketiminato n-butylmagnesium complex with pinacol–
borane in the presence of pyridine derivatives provides facile access to borylated …
borane in the presence of pyridine derivatives provides facile access to borylated …
Atom-efficient regioselective 1, 2-dearomatization of functionalized pyridines by an earth-abundant organolanthanide catalyst
Develo** earth-abundant, non-platinum metal catalysts for high-value chemical
transformations is a critical challenge to contemporary chemical synthesis. Dearomatization …
transformations is a critical challenge to contemporary chemical synthesis. Dearomatization …
Metal-free regio-and chemoselective hydroboration of pyridines catalyzed by 1, 3, 2-diazaphosphenium triflate
N-Heterocyclic phosphenium triflates (NHP-OTf) 1 serve as efficient catalysts for the regio-
and chemoselective hydroboration of pyridines under ambient condition with good …
and chemoselective hydroboration of pyridines under ambient condition with good …
Synthesis, Structure, and Reactivity of a Terminal Magnesium Hydride Compound with a Carbatrane Motif, [TismPriBenz]MgH: A Multifunctional Catalyst for …
The tris [(1-isopropylbenzimidazol-2-yl) dimethylsilyl)] methyl ligand,[TismPriBenz], has been
employed to form the magnesium carbatrane compound,[TismPriBenz] MgH, which …
employed to form the magnesium carbatrane compound,[TismPriBenz] MgH, which …