Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …

Parkinson's disease (PD) is named in honor of James Parkinson, whose classic
monograph,“An Essay on the Shaking Palsy,” written in 1817, has provided an enduring …

In the adult brain, new neurons are continuously generated in the subventricular zone and
dentate gyrus, but it is unknown whether these neurons can replace those lost following …

We describe here the isolation of stem cells from juvenile and adult rodent skin. These cells
derive from the dermis, and clones of individual cells can proliferate and differentiate in …

Parkinson's disease is a widespread condition caused by the loss of midbrain neurons that
synthesize the neurotransmitter dopamine. Cells derived from the fetal midbrain can modify …

The adult brain is extremely vulnerable to various insults. The recent discovery of neural
progenitors in adult mammals, however, raises the possibility of repairing damaged tissue …

Although implantation of fetal dopamine (DA) neurons can reduce parkinsonism in patients,
current methods are rudimentary, and a reliable donor cell source is lacking. We show that …

Objective: To test the effect of IV-injected human bone marrow stromal cells (hMSC) on
neurologic functional deficits after stroke in rats. Methods: Rats were subjected to transient …

There is now evidence to suggest that bone marrow mesenchymal stem cells (MSCs) not
only differentiate into mesodermal cells, but can also adopt the fate of endodermal and …

A recent assertion that new neurons are continually added to the neocortex of adult
macaque monkeys has profound implications for understanding the cellular mechanisms of …