Deep learning in cancer diagnosis, prognosis and treatment selection

KA Tran, O Kondrashova, A Bradley, ED Williams… - Genome Medicine, 2021 - Springer
Deep learning is a subdiscipline of artificial intelligence that uses a machine learning
technique called artificial neural networks to extract patterns and make predictions from …

[HTML][HTML] Addressing bias in big data and AI for health care: A call for open science

N Norori, Q Hu, FM Aellen, FD Faraci, A Tzovara - Patterns, 2021 - cell.com
Artificial intelligence (AI) has an astonishing potential in assisting clinical decision making
and revolutionizing the field of health care. A major open challenge that AI will need to …

Combining machine learning and computational chemistry for predictive insights into chemical systems

JA Keith, V Vassilev-Galindo, B Cheng… - Chemical …, 2021 - ACS Publications
Machine learning models are poised to make a transformative impact on chemical sciences
by dramatically accelerating computational algorithms and amplifying insights available from …

A survey on neural network interpretability

Y Zhang, P Tiňo, A Leonardis… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Along with the great success of deep neural networks, there is also growing concern about
their black-box nature. The interpretability issue affects people's trust on deep learning …

[HTML][HTML] A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity

P Meiser, MA Knolle, A Hirschberger, GP de Almeida… - Cancer Cell, 2023 - cell.com
Type 1 conventional dendritic cells (cDC1) can support T cell responses within tumors but
whether this determines protective versus ineffective anti-cancer immunity is poorly …

Hiplot: a comprehensive and easy-to-use web service for boosting publication-ready biomedical data visualization

J Li, B Miao, S Wang, W Dong, H Xu, C Si… - Briefings in …, 2022 - academic.oup.com
Complex biomedical data generated during clinical, omics and mechanism-based
experiments have increasingly been exploited through cloud-and visualization-based data …

Big data and machine learning algorithms for health-care delivery

KY Ngiam, W Khor - The Lancet Oncology, 2019 - thelancet.com
Analysis of big data by machine learning offers considerable advantages for assimilation
and evaluation of large amounts of complex health-care data. However, to effectively use …

Machine learning in materials science

J Wei, X Chu, XY Sun, K Xu, HX Deng, J Chen, Z Wei… - InfoMat, 2019 - Wiley Online Library
Traditional methods of discovering new materials, such as the empirical trial and error
method and the density functional theory (DFT)‐based method, are unable to keep pace …

Deep learning: new computational modelling techniques for genomics

G Eraslan, Ž Avsec, J Gagneur, FJ Theis - Nature Reviews Genetics, 2019 - nature.com
As a data-driven science, genomics largely utilizes machine learning to capture
dependencies in data and derive novel biological hypotheses. However, the ability to extract …

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

DM Mason, S Friedensohn, CR Weber… - Nature Biomedical …, 2021 - nature.com
The optimization of therapeutic antibodies is time-intensive and resource-demanding,
largely because of the low-throughput screening of full-length antibodies (approximately 1× …