Toward quantitative bio-sensing with nitrogen–vacancy center in diamond

T Zhang, G Pramanik, K Zhang, M Gulka, L Wang… - ACS …, 2021 - ACS Publications
The long-dreamed-of capability of monitoring the molecular machinery in living systems has
not been realized yet, mainly due to the technical limitations of current sensing technologies …

Quantum sensing of free radicals in primary human dendritic cells

L Nie, AC Nusantara, VG Damle, MV Baranov… - Nano …, 2021 - ACS Publications
Free radicals are crucial indicators for stress and appear in all kinds of pathogenic
conditions, including cancer, cardiovascular diseases, and infection. However, they are …

Diamond‐Based Nanoscale Quantum Relaxometry for Sensing Free Radical Production in Cells

A Sigaeva, H Shirzad, FP Martinez, AC Nusantara… - Small, 2022 - Wiley Online Library
Diamond magnetometry makes use of fluorescent defects in diamonds to convert magnetic
resonance signals into fluorescence. Because optical photons can be detected much more …

Fluorescent nanodiamonds for detecting free-radical generation in real time during shear stress in human umbilical vein endothelial cells

R Sharmin, T Hamoh, A Sigaeva, A Mzyk… - ACS …, 2021 - ACS Publications
Free-radical generation is suspected to play a key role in cardiovascular diseases. Another
crucial factor is shear stress. Human umbilical vein endothelial cells (HUVECS), which form …

[HTML][HTML] Detecting the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidants with diamond magnetometry

A Morita, AC Nusantara, A Myzk, FPP Martinez… - Nano Today, 2023 - Elsevier
Free radicals play a key role in the ageing process. However, free radicals are small,
reactive and short lived and thus challenging to measure. We utilize a new technique called …

Diamond color centers in diamonds for chemical and biochemical analysis and visualization

A Mzyk, Y Ong, AR Ortiz Moreno, SK Padamati… - Analytical …, 2021 - ACS Publications
Beyond the sparkle, other properties of diamond have gained increasing attention in the
past few decades among chemists and physicists. Color centers impurities formed by one …

Intracellular quantum sensing of free-radical generation induced by acetaminophen (APAP) in the cytosol, in mitochondria and the nucleus of macrophages

R Sharmin, AC Nusantara, L Nie, K Wu… - ACS …, 2022 - ACS Publications
Acetaminophen overdoses cause cell injury in the liver. It is widely accepted that liver toxicity
is initiated by the reactive N-acetyl-para-aminophenol (APAP) metabolite N-acetyl-p …

The fate of lipid-coated and uncoated fluorescent nanodiamonds during cell division in yeast

A Morita, T Hamoh, FP Perona Martinez, M Chipaux… - Nanomaterials, 2020 - mdpi.com
Fluorescent nanodiamonds are frequently used as biolabels. They have also recently been
established for magnetic resonance and temperature sensing at the nanoscale level. To …

Quantum Sensing Unravels Antioxidant Efficacy Within PCL/Matrigel Skin Equivalents

X Wu, M Koch, FPP Martínez, R Schirhagl… - Small, 2024 - Wiley Online Library
Skin equivalents (SE) that recapitulate biological and mechanical characteristics of the
native tissue are promising platforms for assessing cosmetics and studying fundamental …

Not all cells are created equal–endosomal escape in fluorescent nanodiamonds in different cells

Y Zhang, R Sharmin, A Sigaeva, CWM Klijn, A Mzyk… - Nanoscale, 2021 - pubs.rsc.org
Successful delivery of fluorescent nanodiamonds (FNDs) into the cytoplasm is essential to
many biological applications. Other applications require FNDs to stay within the endosomes …