The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …

Teeth play essential roles in life. Their development relies on reciprocal interactions
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …

Many tissues fold into complex shapes during development. Controlling this process in vitro
would represent an important advance for tissue engineering. We use embryonic tissue …

Ameloblasts are specialized cells derived from the dental epithelium that produce enamel, a
hierarchically structured tissue comprised of highly elongated hydroxylapatite (OHAp) …

Embryonic epithelia achieve complex morphogenetic movements, including in-plane
resha**, bending and folding, through the coordinated action and rearrangement of …

Epithelial invagination is a fundamental module of morphogenesis that iteratively occurs to
generate the architecture of many parts of a develo** organism. By changing the physical …

Tooth number abnormality is one of the most common dental developmental diseases,
which includes both tooth agenesis and supernumerary teeth. Tooth development is …

During vertebrate development, cells must proliferate, move, and differentiate to form
complex shapes. Elucidating the mechanisms underlying the molecular and cellular …

The head represents the most complex part of the body and a distinctive feature of the
vertebrate body plan. This intricate structure is assembled during embryonic development in …

During craniofacial development, the oral epithelium begins as a morphologically
homogeneous tissue that gives rise to locally complex structures, including the teeth …