[HTML][HTML] “What doesn't kill you makes you stronger”: future applications of amyloid aggregates in biomedicine

S Abdelrahman, M Alghrably, JI Lachowicz, AH Emwas… - Molecules, 2020 - mdpi.com
Amyloid proteins are linked to the pathogenesis of several diseases including Alzheimer's
disease, but at the same time a range of functional amyloids are physiologically important in …

Influenza A virus polymerase: an attractive target for next-generation anti-influenza therapeutics

Z Zhou, T Liu, J Zhang, P Zhan, X Liu - Drug Discovery Today, 2018 - Elsevier
Highlights•The structures of influenza polymerase allow the identification of novel anti-
influenza drugs.•The inhibitors targeting influenza polymerase are discussed.•The screening …

In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus

MT Moradi, A Karimi, M Rafieian-Kopaei… - Microbial pathogenesis, 2017 - Elsevier
This research was aimed to evaluate the in vitro antiviral effect and the mechanism of the
effect of Peganum. harmala seeds extract against influenza A virus infection using Madin …

Anti-influenza virus activity and phenolic content of pomegranate (Punica granatum L.) peel extract and fractions

MT Moradi, A Karimi, M Shahrani… - Avicenna journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Background: Influenza virus, associated with high level of morbidity and mortality, has been
recently considered a public health concern while the choices for the control and treatment …

Pomegranate peel extract inhibits internalization and replication of the influenza virus: An in vitro study

MT Moradi, A Karimi, M Rafieian-Kopaei… - Avicenna journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Objective: Influenza virus, which is associated with high level of morbidity and mortality, has
been recently considered a public health concern; however, the methods of choice to control …

Lactobacillus plantarum displaying conserved M2e and HA2 fusion antigens induces protection against influenza virus challenge

WT Yang, GL Yang, L Zhao, YB **, YL Jiang… - Applied microbiology …, 2018 - Springer
Avian influenza virus (AIV) can infect poultry, mammals, and other hosts and causes
enormous economic losses to the global poultry industry. In this study, to develop a novel …

Investigational antiviral therapies for the treatment of influenza

J Yang, Y Huang, S Liu - Expert opinion on investigational drugs, 2019 - Taylor & Francis
Introduction: Influenza viral ribonucleoprotein complexes (vRNPs) play a key role in viral
transcription and replication; hence, the recent development of novel anti-influenza drugs …

The amyloidogenicity of the influenza virus PB1-derived peptide sheds light on its antiviral activity

YA Zabrodskaya, DV Lebedev, MA Egorova… - Biophysical …, 2018 - Elsevier
The influenza virus polymerase complex is a promising target for new antiviral drug
development. It is known that, within the influenza virus polymerase complex, the PB1 …

[HTML][HTML] Production, Passaging Stability, and Histological Analysis of Madin–Darby Canine Kidney Cells Cultured in a Low-Serum Medium

M Cai, Y Le, Z Gong, T Dong, B Liu, M Su, X Li, F Peng… - Vaccines, 2024 - mdpi.com
Madin–Darby canine kidney (MDCK) cells are commonly used to produce cell-based
influenza vaccines. However, the role of the low-serum medium on the proliferation of MDCK …

Advances in Discovery and Design of Anti-influenza Virus Peptides

S Li, X **e, S Zhou, J He - Current Medicinal Chemistry, 2024 - benthamdirect.com
The influenza virus, a well-known pathogen that causes respiratory illness, remains an
important global health threat because of the significant morbidity and mortality rates of …