Into the eye of the cytokine storm
JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …
alike, and while the general notion of an excessive or uncontrolled release of …
The cytokine storm of severe influenza and development of immunomodulatory therapy
Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
Severe influenza remains unusual in its virulence for humans. Complications or ultimately
death arising from these infections are often associated with hyperinduction of …
death arising from these infections are often associated with hyperinduction of …
Clinical features predicting mortality risk in patients with viral pneumonia: the MuLBSTA score
L Guo, D Wei, X Zhang, Y Wu, Q Li, M Zhou… - Frontiers in …, 2019 - frontiersin.org
Objective The aim of this study was to further clarify clinical characteristics and predict
mortality risk among patients with viral pneumonia. Methods A total of 528 patients with viral …
mortality risk among patients with viral pneumonia. Methods A total of 528 patients with viral …
Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans
Protective immunity against influenza virus infection is mediated by neutralizing antibodies,
but the precise role of T cells in human influenza immunity is uncertain. We conducted …
but the precise role of T cells in human influenza immunity is uncertain. We conducted …
[HTML][HTML] Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Fuyang, Anhui, China
R Wang, M Pan, X Zhang, M Han, X Fan, F Zhao… - International Journal of …, 2020 - Elsevier
Objective To investigate the epidemiological and clinical features of patients with COVID-19
in Anhui province of China. Method In this descriptive study, we obtained epidemiological …
in Anhui province of China. Method In this descriptive study, we obtained epidemiological …
Modulatory effects of probiotics during pathogenic infections with emphasis on immune regulation
A Raheem, L Liang, G Zhang, S Cui - Frontiers in immunology, 2021 - frontiersin.org
In order to inhibit pathogenic complications and to enhance animal and poultry growth,
antibiotics have been extensively used for many years. Antibiotics applications not only …
antibiotics have been extensively used for many years. Antibiotics applications not only …
Exuberant fibroblast activity compromises lung function via ADAMTS4
Severe respiratory infections can result in acute respiratory distress syndrome (ARDS).
There are no effective pharmacological therapies that have been shown to improve …
There are no effective pharmacological therapies that have been shown to improve …
[HTML][HTML] Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection
JR Teijaro, KB Walsh, S Cahalan, DM Fremgen… - Cell, 2011 - cell.com
Cytokine storm during viral infection is a prospective predictor of morbidity and mortality, yet
the cellular sources remain undefined. Here, using genetic and chemical tools to probe …
the cellular sources remain undefined. Here, using genetic and chemical tools to probe …
Influenza virus activates inflammasomes via its intracellular M2 ion channel
Influenza virus, a negative-stranded RNA virus that causes severe illness in humans and
animals, stimulates the inflammasome through the Nod-like receptor NLRP3. However, the …
animals, stimulates the inflammasome through the Nod-like receptor NLRP3. However, the …