Diagnosis of neonatal sepsis: the role of inflammatory markers

J Eichberger, E Resch, B Resch - Frontiers in pediatrics, 2022 - frontiersin.org
This is a narrative review on the role of biomarkers in the diagnosis of neonatal sepsis. We
describe the difficulties to obtain standardized definitions in neonatal sepsis and discuss the …

[PDF][PDF] Neonatal sepsis

IO Odabasi, A Bulbul - Şişli Etfal Hastanesi Tip Bülteni, 2020 - jag.journalagent.com
Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period.
Clinical manifestations range from subclinical infection to severe local or systemic infection …

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects

ST Liao, C Han, DQ Xu, XW Fu, JS Wang… - Nature …, 2019 - nature.com
Activated macrophages switch from oxidative phosphorylation to aerobic glycolysis, similar
to the Warburg effect, presenting a potential therapeutic target in inflammatory disease. The …

Biomarkers for diagnosis of neonatal sepsis: a literature review

D Sharma, N Farahbakhsh, S Shastri… - The Journal of Maternal …, 2018 - Taylor & Francis
Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

Neonatal sepsis: an old problem with new insights

BA Shah, JF Padbury - Virulence, 2014 - Taylor & Francis
Neonatal sepsis continues to be a common and significant health care burden, especially in
very-low-birth-weight infants (VLBW< 1500 g). Though intrapartum antibiotic prophylaxis has …

The challenges of neonatal sepsis management

RS Procianoy, RC Silveira - Jornal de pediatria, 2020 - SciELO Brasil
Objectives To present current evidence on the etiology, risk factors, diagnosis, and
management of early and late neonatal sepsis. Source of data Non-systematic review of the …

Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

Potential biomarkers for effective screening of neonatal sepsis infections: an overview

N Chauhan, S Tiwari, U Jain - Microbial pathogenesis, 2017 - Elsevier
Neonatal sepsis, a clinical disorder developed by bacterial blood stream infections (BSI) in
neonates, is one of the serious global public health problems that must be addressed. More …

Translational research and biomarkers in neonatal sepsis

JR Delanghe, MM Speeckaert - Clinica chimica acta, 2015 - Elsevier
As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Neonatal sepsis and inflammatory mediators

J Reis Machado, DF Soave, MV da Silva… - Mediators of …, 2014 - Wiley Online Library
Neonatal sepsis is a major cause of morbidity and mortality and its signs and symptoms are
nonspecific, which makes the diagnosis difficult. The routinely used laboratory tests are not …