The versatile pharmaceutical material cyclodextrin's (CDs) are classified into hydrophilic,
hydrophobic, and ionic derivatives. By the early 1950s the basic physicochemical …

Cyclodextrins have proven themselves to be useful functional excipients. Cyclodextrin
derivatives can be hydrophilic or relatively lipophilic based on their substitution and these …

Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …

Oral transmucosal drug delivery (OTDD) dosage forms have been available since the
1980s. In contrast to the number of actives currently delivered locally to the oral cavity, the …

Delivery of drugs by the oral route remains the most spread route to administer medicines to
patients. The manuscript takes into consideration the most important organs of the digestive …

To improve therapeutic effects and compatibility of patients, controlled release tablet
systems based on polymers are of great interest for pharmaceutical technologies. Poly …

Background: Drug delivery via oral mucosa is an alternative method of systemic
administration for various classes of therapeutic agents. Among the oral mucosae, buccal …

Carvedilol (Table I) is a non-selective β-blocker indicated in the treatment of mild to
moderate congestive heart failure. It also has vasodilating properties that are mainly …

The objective of this study was to design and in vitro–in vivo evaluate oral nanocapsules
prepared from amphiphilic cyclodextrins (CDs) or poly-ε-caprolactone (PCL) for the effective …

Abstract Raloxifene hydrochloride (R-HCl), a BCS class II drug, remains a mainstay in the
prevention and pharmacologic therapy of osteoporosis. Its absolute bioavailability, however …