Gastric cancer: a comprehensive review of current and future treatment strategies
Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …
The caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer
M Jiang, L Qi, L Li, Y Li - Cell death discovery, 2020 - nature.com
Apoptosis has long been recognized as a mechanism that kills the cancer cells by cytotoxic
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …
Drug resistance in cancer: mechanisms and tackling strategies
Drug resistance developed towards conventional therapy is one of the important reasons for
chemotherapy failure in cancer. The various underlying mechanism for drug resistance …
chemotherapy failure in cancer. The various underlying mechanism for drug resistance …
[HTML][HTML] Cancer-associated fibroblasts-derived IL-8 mediates resistance to cisplatin in human gastric cancer
J Zhai, J Shen, G **e, J Wu, M He, L Gao, Y Zhang… - Cancer letters, 2019 - Elsevier
Chemoresistance remains the major obstacle to achieve optimal prognosis in gastric cancer
patients, and the underlying molecular mechanisms of cancer-associated fibroblasts (CAFs) …
patients, and the underlying molecular mechanisms of cancer-associated fibroblasts (CAFs) …
Overcoming multidrug resistance in cancer: Recent progress in nanotechnology and new horizons
Multidrug resistance (MDR), defined as the ability of cancer cells to gain resistance to both
conventional and novel chemotherapy agents, is an important barrier in treating …
conventional and novel chemotherapy agents, is an important barrier in treating …
Update on gastric cancer treatments and gene therapies
Gastric cancer is an active topic of clinical and basic research due to high morbidity and
mortality. To date, gastrectomy and chemotherapy are the only therapeutic options for gastric …
mortality. To date, gastrectomy and chemotherapy are the only therapeutic options for gastric …
Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …
[HTML][HTML] Exosomes serve as nanoparticles to deliver anti-miR-214 to reverse chemoresistance to cisplatin in gastric cancer
X Wang, H Zhang, M Bai, T Ning, S Ge, T Deng, R Liu… - Molecular therapy, 2018 - cell.com
Chemoresistance is one of the causes of adverse effects in gastric cancer, including a poor
response to cisplatin (DDP). Exosomes loaded with microRNA (miRNA), mRNA, and other …
response to cisplatin (DDP). Exosomes loaded with microRNA (miRNA), mRNA, and other …
PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells
ZN Navaei, G Khalili-Tanha, AS Zangouei… - Oncology …, 2022 - pmc.ncbi.nlm.nih.gov
Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …
[HTML][HTML] Tumor heterogeneity of gastric cancer: From the perspective of tumor-initiating cell
JP Gao, W Xu, WT Liu, M Yan… - World Journal of …, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) remains one of the most common and malignant types of cancer due to
its rapid progression, distant metastasis, and resistance to conventional chemotherapy …
its rapid progression, distant metastasis, and resistance to conventional chemotherapy …