Macrophages in immunoregulation and therapeutics
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …
and are a vital part of the innate immune system for host defense against many pathogens …
Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
Targeting macrophages in cancer immunotherapy
Z Duan, Y Luo - Signal transduction and targeted therapy, 2021 - nature.com
Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
[HTML][HTML] The M1 and M2 paradigm of macrophage activation: time for reassessment
FO Martinez, S Gordon - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Macrophages are endowed with a variety of receptors for lineage-determining growth
factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues …
factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues …
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
Metabolic inflammation and insulin resistance in obesity
H Wu, CM Ballantyne - Circulation research, 2020 - Am Heart Assoc
Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
Roles of tumor-associated macrophages in anti-PD-1/PD-L1 immunotherapy for solid cancers
H Zhang, L Liu, J Liu, P Dang, S Hu, W Yuan, Z Sun… - Molecular Cancer, 2023 - Springer
In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …
Macrophages: the good, the bad, and the gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …
sterile inflammation. In this review, we will compile and interpret recent findings on the …
Metal-based photosensitizers as inducers of regulated cell death mechanisms
Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …
discovered and were found to improve cancer treatment. Although there are several reviews …
Immune attack: the role of inflammation in Alzheimer disease
The past two decades of research into the pathogenesis of Alzheimer disease (AD) have
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …