Pathomechanisms of blood‐brain barrier disruption in ALS
The blood‐brain barrier (BBB) and the blood‐spinal cord barrier (BSCB) are responsible for
controlling the microenvironment within neural tissues in humans. These barriers are …
controlling the microenvironment within neural tissues in humans. These barriers are …
From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline
Amyotrophic lateral sclerosis (ALS) and Frontotemporal Degeneration (FTD) are
neurodegenerative disorders, related by deterioration of motor and cognitive functions and …
neurodegenerative disorders, related by deterioration of motor and cognitive functions and …
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
P Kaufmann, JLP Thompson, G Levy… - Annals of Neurology …, 2009 - Wiley Online Library
Objective Amyotrophic lateral sclerosis (ALS) is a devastating, and currently incurable,
neuromuscular disease in which oxidative stress and mitochondrial impairment are …
neuromuscular disease in which oxidative stress and mitochondrial impairment are …
[HTML][HTML] Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study
ProGas Study Group - The Lancet Neurology, 2015 - Elsevier
Background Gastrostomy feeding is commonly used to support patients with amyotrophic
lateral sclerosis who develop severe dysphagia. Although recommended by both the …
lateral sclerosis who develop severe dysphagia. Although recommended by both the …
Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options
S Körner, M Hendricks, K Kollewe, A Zapf, R Dengler… - BMC neurology, 2013 - Springer
Background Weight loss is a frequent feature in the motor neuron disease Amyotrophic
lateral sclerosis (ALS). In this study we investigated possible causes of weight loss in ALS …
lateral sclerosis (ALS). In this study we investigated possible causes of weight loss in ALS …
Nutrient effects on motor neurons and the risk of amyotrophic lateral sclerosis
PS Goncharova, TK Davydova, TE Popova… - Nutrients, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is an incurable chronic progressive neurodegenerative
disease with the progressive degeneration of motor neurons in the motor cortex and lower …
disease with the progressive degeneration of motor neurons in the motor cortex and lower …
Nutritional and metabolic support in patients with amyotrophic lateral sclerosis
M Muscaritoli, I Kushta, A Molfino, M Inghilleri… - Nutrition, 2012 - Elsevier
Amyotrophic lateral sclerosis (ALS) is the most common form of progressive motor neuron
disease and the most devastating neurodegenerative disorder. ALS is characterized by …
disease and the most devastating neurodegenerative disorder. ALS is characterized by …
Integrated omic analysis delineates pathways modulating toxic TDP-43 protein aggregates in amyotrophic lateral sclerosis
S Rajaratnam, AP Soman, KS Phalguna, SS Pradhan… - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a multi-systemic, incurable, amyloid disease affecting
the motor neurons, resulting in the death of patients. The disease is either sporadic or …
the motor neurons, resulting in the death of patients. The disease is either sporadic or …
[HTML][HTML] Body mass index and dietary intervention: implications for prognosis of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is an adult onset, neurodegenerative disease that is
characterized by the loss of upper (corticospinal) and lower motor neurons. ALS is a …
characterized by the loss of upper (corticospinal) and lower motor neurons. ALS is a …
Gastrostomy use in motor neurone disease (MND): a review, meta-analysis and survey of current practice
Gastrostomy feeding is commonly used to support MND patients with dysphagia. In this
paper we review three main methods of gastrostomy insertion (PEG, RIG, PIG); conduct a …
paper we review three main methods of gastrostomy insertion (PEG, RIG, PIG); conduct a …