Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Tumor blood vessels are a key target for cancer therapeutic management. Tumor cells
secrete high levels of pro-angiogenic factors which contribute to the creation of an abnormal …

Since the initial clinical approval in the late 1990s and remarkable anticancer effects for
certain types of cancer, molecular targeted therapy utilizing small molecule agents or …

Although pulmonary fibrosis can occur in the absence of a clear‐cut inciting agent, and
without a clinically clear initial acute inflammatory phase, it is more commonly associated …

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Upon activation, platelets secrete more than 300 active substances from their intracellular
granules. Platelet dense granule components, such as ADP and polyphosphates, contribute …

Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …

Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the
cell-cell interactions that imprint the tissue-specific identities of macrophages in their …

In the mammalian skeletal system, osteogenesis and angiogenesis are intimately linked
during bone growth and regeneration in bone modeling and during bone homeostasis in …

The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …