Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

Since the first two complete bacterial genome sequences were published in 1995, the
science of bacteria has dramatically changed. Using third-generation DNA sequencing, it is …

Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

Fast and accurate identification and ty** of pathogens are essential for effective
surveillance and outbreak detection. The current routine procedure is based on a variety of …

Genomics and whole genome sequencing (WGS) have the capacity to greatly enhance
knowledge and understanding of infectious diseases and clinical microbiology. The growth …

Hospitals worldwide are facing an increasing incidence of hard-to-treat infections. Limiting
infections and providing patients with optimal drug regimens require timely strain …

Objectives Next generation sequencing (NGS) may be an alternative to phenotypic
susceptibility testing for surveillance and clinical diagnosis. However, current bioinformatics …

Shigella spp. and Escherichia coli are closely related; both belong to the family
Enterobacteriaceae. Phenotypically, Shigella spp. and E. coli share many common …

Antibiotic resistance is a global problem which affects human health. The imprudent use of
antibiotics (medicine, agriculture, aquaculture, and food industry) has resulted in the broader …

Recent advances in whole genome sequencing have made the technology available for
routine use in microbiological laboratories. However, a major obstacle for using this …