Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via
a balance between bone formation by osteoblasts and resorption by osteoclasts. These …

The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Actomyosin-mediated contractility is a highly conserved mechanism for generating
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …

This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly
nonlinear mechanical properties. While the linear elasticity of the matrix can significantly …

The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

The cytoskeleton is the major mechanical structure of the cell; it is a complex, dynamic
biopolymer network comprising microtubules, actin, and intermediate filaments. Both the …

The recent convergence between physics and biology has led many physicists to enter the
fields of cell and developmental biology. One of the most exciting areas of interest has been …

Morphogenesis, tumor formation, and wound healing are regulated by tissue rigidity. Focal
adhesion behavior is locally regulated by stiffness; however, how cells globally adapt …

Cellular responses to mechanical forces are crucial in embryonic development and adult
physiology, and are involved in numerous diseases, including atherosclerosis …