The involvement of nitric oxide synthase neurons in enteric neuropathies
Nitric oxide (NO), produced by the neural nitric oxide synthase enzyme (nNOS) is a
transmitter of inhibitory neurons supplying the muscle of the gastrointestinal tract …
transmitter of inhibitory neurons supplying the muscle of the gastrointestinal tract …
Chagas' disease and the autoimmunity hypothesis
F Kierszenbaum - Clinical microbiology reviews, 1999 - Am Soc Microbiol
The notion that the pathology of Chagas' disease has an autoimmune component was
initially based on the finding of circulating antibodies binding heart tissue antigens in …
initially based on the finding of circulating antibodies binding heart tissue antigens in …
Induction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry
E Cunha-Neto, AM Bilate, KV Hyland, SG Fonseca… - …, 2006 - Taylor & Francis
Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in
Latin America, one third of whom will develop chronic Chagas disease cardiomyopathy …
Latin America, one third of whom will develop chronic Chagas disease cardiomyopathy …
Antibodies in the pathogenesis of hypertension
CT Chan, M Lieu, BH Toh, TS Kyaw… - BioMed Research …, 2014 - Wiley Online Library
It has long been known that circulating levels of IgG and IgM antibodies are elevated in
patients with essential and pregnancy‐related hypertension. Recent studies indicate these …
patients with essential and pregnancy‐related hypertension. Recent studies indicate these …
Cardiac myosin autoimmunity in acute Chagas' heart disease
Infection with Trypanosoma cruzi, the agent of Chagas' disease, may induce antibodies and
T cells reactive with self antigens (autoimmunity). Because autoimmunity is generally …
T cells reactive with self antigens (autoimmunity). Because autoimmunity is generally …
[HTML][HTML] Ca2+ currents in cardiac myocytes: old story, new insights
Calcium is a ubiquitous second messenger which plays key roles in numerous physiological
functions. In cardiac myocytes, Ca2+ crosses the plasma membrane via specialized voltage …
functions. In cardiac myocytes, Ca2+ crosses the plasma membrane via specialized voltage …
[PDF][PDF] Functional autoantibody diseases: Basics and treatment related to cardiomyopathies
NP Becker, P Goettel, J Mueller… - … Biosci (Landmark Ed …, 2019 - article.imrpress.com
Protein- mediated enamel mineralization Page 1 48 Functional autoantibody diseases: Basics
and treatment related to cardiomyopathies Niels-Peter Becker1, Peter Goettel1, Johannes …
and treatment related to cardiomyopathies Niels-Peter Becker1, Peter Goettel1, Johannes …
Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential
L Wang, K Lu, H Hao, X Li, J Wang, K Wang, J Wang… - PloS one, 2013 - journals.plos.org
It has been recognized that changes in mitochondrial structure plays a key role in
development of cardiac dysfunction, and autophagy has been shown to exert maintenance …
development of cardiac dysfunction, and autophagy has been shown to exert maintenance …
Drug‐like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function
LR Herda, SB Felix, F Boege - British journal of pharmacology, 2012 - Wiley Online Library
Antibodies against cholinergic and adrenergic receptors (adrenoceptors) are frequent in
serum of patients with chronic heart failure. Their prevalence is associated with Chagas' …
serum of patients with chronic heart failure. Their prevalence is associated with Chagas' …
Views on the autoimmunity hypothesis for Chagas disease pathogenesis
F Kierszenbaum - FEMS Immunology & Medical Microbiology, 2003 - academic.oup.com
Initially, the notion that the pathogenesis of Chagas disease has an autoimmune component
was based on the finding that sera from Trypanosoma cruzi-infected patients or laboratory …
was based on the finding that sera from Trypanosoma cruzi-infected patients or laboratory …